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23-056 XIAP, active

XIAP, active MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Enzyme Assays Entrez Gene Number: NM_001167
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23-056
10 µg  
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      概述

      Replacement Information
      Description
      Catalogue Number23-056
      Brand Family Upstate
      Trade Name
      • Upstate
      DescriptionXIAP, active
      Alternate Names
      • Baculoviral IAP repeat-containing protein 4 (BIRC4)
      • IAP-like protein
      • Inhibitor of apoptosis protein 3 (API3)
      Background InformationX-linked inhibitor of apoptosis (XIAP) is one of a group of intracellular proteins which have been shown to act as endogenous inhibitors of caspases, the enzymatic effectors of apoptosis. XIAP possesses a C-terminal RING domain that functions as an E3 ubiquitin ligase and is able to ubiquitinate a variety of substrates thereby affecting a broad range of cellular activities beyond apoptotic suppression. There is evidence that XIAP plays a significant role in cell division, morphogenesis, heavy metal homeostasis, NF-kB activation and MAP kinase signalling. XIAP expression has been shown to be elevated in several malignancies and so is considered a promising target in anticancer therapies.
      References
      Product Information
      Quality LevelMQ100
      Applications
      Key Applications
      • Enzyme Assays
      Biological Information
      Cascade ComponentE3
      Entrez Gene Number
      Purification MethodPurified using glutathione sepharose, followed by gel filtration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Packaging Information
      Material Size10 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      产品目录编号 GTIN
      23-056 04053252919039

      相关产品和应用

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      产品目录编号 描述  
      23-056M XIAP, active 显示价格及库存情况

      产品族

      Ubiquitin Proteasome System: Enzymes and Substrates

      Millipore has removed the complexity of Ubiquitination by providing functionally validated enzymes and substrates, making the pathway readily accessible for research and drug discovery.
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      种类

      Life Science Research > Proteins and Enzymes > Other Proteins