Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
Our range of embedding media includes highly pure Histosec® selected paraffin, which is enriched with polymers and available with or without the entrainer DMSO.
We offer a broad range of CE-certified auxiliaries for histology, including products for fixation, histoprocessing, embedding, dehydration and mounting of specimens.
Post-translational methylation of arginine and lysine residues is thought to be an important control mechanism for the regulation of protein expression in eukaryotes.
Methylation as a part of signal transduction is carried out by methyltransferase enzymes that reversibly add methyl groups to the carboxyl groups of proteins and DNA, forming methyl esters.
The products we create help our customers improve people's lives every day, but we recognize that every product we make also has an environmental impact.
Histone modifications regulate DNA transcription, repair, recombination, and replication, and can alter local chromatin architecture. Understanding histone modifications is key to uncovering epigenetic mechanisms of gene regulation. Merck grasps the complexity of this research and provides a growing line of kits, antibodies, and assays for studying histones and their modifications. Merck offers over 600 validated antibodies, recombinant proteins, and kits to analyze histone and histone-variant phosphorylation, methylation, acetylation, ubiquitination, and citrullination-the most widely studied histone modifications in epigenetics today.