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Merck

AB1952P

Anti-Integrin beta 1 (CD29) Antibody

CHEMICON®, rabbit polyclonal

Sinónimos:

CD29

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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
human, rat, pig, mouse
Application:
IP, WB
Citations:
8
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Nombre del producto

Anti-Integrin β1 Antibody, cytosolic, Chemicon®, from rabbit

biological source

rabbit

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat, pig, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... ITGB1(3688)

General description

130kDa

Immunogen

Epitope: cytosolic
Synthetic peptide corresponding to the C-terminus of human integrin beta 1 (a.a. CTTVVNPKYEGK)

Application

Detect Integrin β1 using this Anti-Integrin β1 Antibody, cytosolic validated for use in IP & WB.
Western blot: 1-2μg/mL for detection in whole cell lysate. The antibody is effective against reduced (MW = 130kDa) and non-reduced (MW = 110kDa) proteins.

Immunoprecipitation

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Reactive with human, mouse, and rat integrin beta-1, as confirmed by western blot. Not reactive with other integrins.

Physical form

Format: Purified
Protein A Purified immunoglobulin. Liquid in PBS containing 0.1% sodium azide.

Analysis Note

Control
U251 cell line Skin (Basement Membrane)

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Jean-Baptiste Oudart et al.
Cell adhesion & migration, 15(1), 215-223 (2021-07-27)
We previously demonstrated that F4 peptide (CNPEDCLYPVSHAHQR) from collagen XIX was able to inhibit melanoma cell migrationin vitro and cancer progression in a mouse melanoma model. The aim of the present work was to study the anti-angiogenic properties of F4 peptide. We demonstrated that F4
Xiaoming Bai et al.
Scientific reports, 4, 6538-6538 (2014-10-08)
Prostaglandin E2 (PGE2) has been implicated in cell invasion in hepatocellular carcinoma (HCC), via increased β1-integrin expression and cell migration; however, the mechanism remains unclear. PGE2 exerts its effects via four subtypes of the E prostanoid receptor (EP receptor 1-4).
Alexia Vautrin-Glabik et al.
Frontiers in cell and developmental biology, 8, 775-775 (2020-08-28)
Angiogenesis is defined as the formation of new capillaries by sprouting from the pre-existing microvasculature. It occurs in physiological and pathological processes particularly in tumor growth and metastasis. α1, α2, α3, and α6 NC1 domains from type IV collagen were
Jinshun Pan et al.
Scientific reports, 6, 33823-33823 (2016-09-23)
Cyclooxygenase-2 (COX-2) has been implicated in cell invasion in non-small-cell lung cancer (NSCLC). However, the mechanism is unclear. The present study investigated the effect of COX-2 on β1-integrin expression and cell invasion in NSCLC. COX-2 and β1-integrin were co-expressed in
Konstantina Karamanou et al.
The FEBS journal, 287(22), 4862-4880 (2020-03-12)
The small leucine-rich proteoglycan lumican regulates estrogen receptors (ERs)-associated functional properties of breast cancer cells, expression of matrix macromolecules, and epithelial-to-mesenchymal transition. However, it is not known whether the ER-dependent lumican effects on breast cancer cells are related to the

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SKUGTIN
AB1952P04053252621383

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