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Merck

S5761

Bicarbonato de sodio

powder, BioReagent, Molecular Biology, suitable for cell culture, suitable for insect cell culture

Sinónimos:

Sodium hydrogen carbonate, soda bicarbonate

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Fórmula lineal:
NaHCO3
Número CAS:
Peso molecular:
84.01
UNSPSC Code:
12161702
NACRES:
NA.75
PubChem Substance ID:
EC Number:
205-633-8
Beilstein/REAXYS Number:
4153970
MDL number:
Assay:
99.5-100.5%
Grade:
Molecular Biology
Form:
powder
Solubility:
water: soluble 100 mg/mL
Servicio técnico
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grade

Molecular Biology

Quality Segment

product line

BioReagent

assay

99.5-100.5%

form

powder

quality

300

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable

pH

6.8-7.4

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

solubility

water: soluble 100 mg/mL

density

2.16 g/mL at 25 °C (lit.)

SMILES string

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

General description

Sodium bicarbonate is broadly used as a physiological buffer in cell culture applications. The pKa for bicarbonate <-> carbonic acid reaction is 6.4 The pKa for bicarbonate <-> carbonate reaction is 10.3. Sodum bicarbonate has two pKas, 6.4 and 10.3. It is broadly used as an physiological buffer in in vitro applications.

Application

Sodium bicarbonate has been used:
  • as a component of bovine embryo culture system during in vitro maturation, fertilization, and culture (IVMFC)
  • as a component of a 1:1 mixture of Dulbecco′s modified Eagle′s medium and Ham′s nutrient mixture F-12 during the culture of bovine microvascular endothelial cells
  • as a component of ITS (insulin transferrin and selenite) medium used during the isolation of dopamine neurons from human embryonic stem cells
  • as a component of medium used for cell culture of human embryonic kidney cells
  • as a component of Beltsville thawing solution used for the dilution of semen


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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