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Merck

SML0503

9(S)-HODE

≥98% (HPLC), metabolite of linoleic acid, solution

동의어(들):

9S-Hydroxy-10E,12Z-octadecadienoic acid

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제품정보 (DICE 배송 시 비용 별도)

실험식(Hill 표기법):
C18H32O3
CAS 번호:
Molecular Weight:
296.44
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
200-578-6
MDL number:
Assay:
≥98% (HPLC)
Form:
solution
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제품 이름

9(S)-HODE, ≥98% (HPLC)

Quality Segment

assay

≥98% (HPLC)

form

solution

concentration

1 mg/mL in ethanol

color

colorless to light yellow

shipped in

wet ice

storage temp.

−20°C

SMILES string

CCCCC/C=C\C=C\[C@@H](O)CCCCCCCC(O)=O

InChI

1S/C18H32O3/c1-2-3-4-5-6-8-11-14-17(19)15-12-9-7-10-13-16-18(20)21/h6,8,11,14,17,19H,2-5,7,9-10,12-13,15-16H2,1H3,(H,20,21)/b8-6-,14-11+/t17-/m1/s1

InChI key

NPDSHTNEKLQQIJ-UINYOVNOSA-N

Biochem/physiol Actions

9(S)-HODE is a pro-inflammatory linoleic acid lipoxygenation product.
9(S)-HODE is produced by the lipoxygenation of linoleic acid. It is a major component of plasma oxidized low-density lipoprotein. 9-HODE has been shown to stimulate cell proliferation and and extracellular matrix synthesis in human mesangial cells via PPARgamma. Pro-inflammatory effects of 9-HODE, acting through the receptor GPR132, can contribute to atherosclerosis progression. 9-HODE has also been shown to activate spinal TRPV1, leading to inflammatory hyperalgesia.

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.


pictograms

FlameExclamation mark

signalword

Danger

hcodes

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2

저장 등급

3 - Flammable liquids

wgk

WGK 1

flash_point_f

57.2 °F - closed cup

flash_point_c

14.0 °C - closed cup



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시험 성적서(COA)

Lot/Batch Number

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