2017 Technical ADC Symposium
Thursday, October 19, 2017 8:00 am - 4:30 pm
Reception & Dinner
Thursday, October 19, 2017 6:00 pm- 10:00 pm
You are invited to participate, in Merck’s 2017 Technical ADC Symposium and networking dinner.
This one-day Symposium is a unique opportunity to discover latest trends in ADC development and processing. Learn, share and discuss today’s advancements with your peers and subject matter experts of the industry during refreshment breaks and dinner.
Agenda*
| 8:00 - 8:30 AM | Registration & Coffee | |
| 8:30 - 9:00 AM | Introduction | |
| Welcome | ||
| Dr. Matthias Bucerius, Vice President, Head of Actives & Formulation, Merck KGaA, Darmstadt, Germany | ||
| Chair | ||
| Dr. Michael Kaufman, Senior Vice President, CMC, Mersana Therapeutics | ||
| 9:00 - 12:30 PM | Technical Presentations - Advancing ADC Development | |
| CMC Challenges with Next-Generation ADCs | ||
| Laura Packer, Staff Engineer, Biologics CMC Group, Takeda | ||
| Discovery, Development, and Production of Homogeneous ADC Molecules Using XPress CF+ Cell-Free Expression Technology | ||
| Dr. Heidi Hoffmann, Senior Director, Supply Chain and CMC Lead, Sutro Biopharma | ||
| The Pros and Cons of Lysine, Cysteine, and BTG Glutamine Conjugations | ||
| Dr. Thomas Nittoli, Director, R&D Chemistry, Regeneron Pharmaceuticals | ||
| Development and Manufacture of a Novel Drug-Linker: Enabling High DAR ADCs | ||
| Dr. Michael Kaufman, Senior Vice President, CMC, Mersana Therapeutics | ||
| Best Practices in the Externalization of the ADC Supply Chain | ||
| Dr. Vincent Turula, Director, External Supply, Pfizer | ||
| Optimization of Cell Culture Processes to Meet ADC Challenges | ||
| Michael McGlothlen, Head of Upstream Development, Biodevelopment Services North America, MilliporeSigma | ||
| 12:30 - 2:00 PM | Lunch Break & Networking | |
| 2:00 - 3:45 PM | Technology Insights & Processing Solutions | |
| Introduction to the MLab® Collaboration Center | ||
| Susan Gambale, Technical Operations, MilliporeSigma | ||
| MLab™ Collaboration Center tour | ||
| Susan Gambale & Mary Robinette, MilliporeSigma | ||
| MilliporeSigma Poster Presentations: | ||
Mobius Technology Supporting ADC Processing | ||
Adam Sokolnicki | ||
Single-use ADC Equipment: Lab Scale-up to GMP Production | ||
Dr. Gang Yao | ||
Demonstration of Solvent Compatibility and Extractables Profile for use of Mobius® Assemblies in ADC Processing | ||
Elizabeth Goodrich | ||
Evaluation of a Novel Single Use TFF Capsule | ||
Jonathan Steen | ||
| 3:45 - 4:30 PM | Coffee & networking | |
| 4:30 - 6:00 PM | Free time & shuttle to dinner venue | |
| 6:00 - 10:00 PM | Reception & dinner at the Top of The Hub Boston |
*Agenda subject to change. The event is free; registration is mandatory and space is limited to 50 attendees. Attendance to the “2017 Technical ADC Symposium” is limited and available to pharma/biopharma manufacturers and academics only. The offer does not extend to any company that provides products or services to the pharma/biopharma industry. MilliporeSigma reserves the right to revoke or refuse participation at any times.
Refreshments are provided courtesy of MilliporeSigma. Travel costs, hotel accommodations and any other costs incurred are at the expense of the attendees.
Venue: MilliporeSigma in Burlington, MA
The Symposium will take place at our brand-new MilliporeSigma facility, showcasing our M Lab™ Collaboration Center.
400 Summit Drive*
Burlington, MA 01803
USA
*Some GPS systems have not been updated with the new street name. If your GPS system does not recognize Summit Drive, please enter:
400 Wheeler Road, Burlington, MA 01803 and you should be able to find the location.
Dinner Venue: Top of The Hub, Boston
Prudential Tower
800 Boylston Street
Boston, MA 02199
The one-day event will include:
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MilliporeSigma
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Merck KGaA, Darmstadt, Germany