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05-23-0070 α-Helical Corticotropin Releasing Factor 9-41

05-23-0070
  
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Áttekintés

Replacement Information

Kulcsspecifikációk táblázata

CAS #Empirical Formula
99658-03-4C₁₆₆H₂₇₄N₄₆O₅₃S₂
Description
Overview

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A stable analog of porcine motilin with full biological activity. Acts as a potent antagonist of CRF receptors. Blocks stress-induced hypophagia and weight loss.
Catalogue Number05-23-0070
Brand Family Calbiochem®
SynonymsCRF Antagonist; α-Helical CRF (9-41)
References
ReferencesSamgin, G.N., et al. 1999. Am. J. Physiol. 276, R1461.
Moody, T.W., et al. 1994. Peptides 15, 281.
Milton, N.G., et al. 1993. J. Physiol. 465, 415.
Rivier, J., et al. 1984. Science 224, 889.
Product Information
CAS number99658-03-4
FormWhite to off-white lyophilized solid
Hill FormulaC₁₆₆H₂₇₄N₄₆O₅₃S₂
Chemical formulaC₁₆₆H₂₇₄N₄₆O₅₃S₂
Hygroscopic Hygroscopic
Sold on the basis of peptide contentY
Applications
Biological Information
Purity≥97% by HPLC
Physicochemical Information
Peptide ContentY
Peptide SequenceH-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH₂
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

α-Helical Corticotropin Releasing Factor 9-41 Certificates of Analysis

TitleLot Number
05-23-0070

References

Hivatkozások áttekintése
Samgin, G.N., et al. 1999. Am. J. Physiol. 276, R1461.
Moody, T.W., et al. 1994. Peptides 15, 281.
Milton, N.G., et al. 1993. J. Physiol. 465, 415.
Rivier, J., et al. 1984. Science 224, 889.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-May-2008 JSW
SynonymsCRF Antagonist; α-Helical CRF (9-41)
DescriptionAn analog of corticotropin-releasing factor that acts as a potent and competetive antagonist of CRF receptors.
FormWhite to off-white lyophilized solid
CAS number99658-03-4
Chemical formulaC₁₆₆H₂₇₄N₄₆O₅₃S₂
Peptide SequenceH-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Met-Leu-Glu-Met-Ala-Lys-Ala-Glu-Gln-Glu-Ala-Glu-Gln-Ala-Ala-Leu-Asn-Arg-Leu-Leu-Leu-Glu-Glu-Ala-NH₂
Purity≥97% by HPLC
Solubility5% acetic acid (5 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesSamgin, G.N., et al. 1999. Am. J. Physiol. 276, R1461.
Moody, T.W., et al. 1994. Peptides 15, 281.
Milton, N.G., et al. 1993. J. Physiol. 465, 415.
Rivier, J., et al. 1984. Science 224, 889.