218740 Caspase-2 Substrate I, Fluorogenic

218740
  
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      Áttekintés

      Replacement Information
      Description
      Overview

      This product has been discontinued.





      A fluorogenic substrate for the detection of caspase-2 (ICH-1). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.

      Catalogue Number218740
      Brand Family Calbiochem®
      SynonymsZ-VDVAD-AFC
      References
      ReferencesIto, A., et al. 1999. Biochim. Biophys. Acta 1452, 263.
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.
      Product Information
      FormLyophilized
      Hill FormulaC₃₉H₄₅F₃N₆O₁₃
      Chemical formulaC₃₉H₄₅F₃N₆O₁₃
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Emission max.
      Excitation max.
      Peptide SequenceZ-Val-Asp-Val-Ala-Asp-AFC
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Caspase-2 Substrate I, Fluorogenic MSDS

      Title

      Safety Data Sheet (SDS) 

      Caspase-2 Substrate I, Fluorogenic Certificates of Analysis

      TitleLot Number
      218740

      References

      Hivatkozások áttekintése
      Ito, A., et al. 1999. Biochim. Biophys. Acta 1452, 263.
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-June-2008 RFH
      SynonymsZ-VDVAD-AFC
      DescriptionA fluorogenic substrate for detection of caspase-2 (ICH-1). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation max: ~400 nm; emission max: ~505 nm).
      FormLyophilized
      Chemical formulaC₃₉H₄₅F₃N₆O₁₃
      Peptide SequenceZ-Val-Asp-Val-Ala-Asp-AFC
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage -20°C
      Protect from moisture
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesIto, A., et al. 1999. Biochim. Biophys. Acta 1452, 263.
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Talanian, R.V., et al. 1997. J. Biol. Chem. 272, 9677.