218721 Caspase Substrate I, Fluorogenic

218721
  
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      Áttekintés

      Replacement Information
      Description
      OverviewFluorogenic caspase-1 substrate. May also be used as a caspase-3, caspase-4, or caspase-7 substrate. Reaction can be monitored by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
      Catalogue Number218721
      Brand Family Calbiochem®
      SynonymsAc-VAD-AFC
      References
      ReferencesSusin, S.A., et al. 1999. J. Exp. Med. 189, 381.
      Thornberry, N.A. and Lazebnik, Y. 1998. Science 281, 1312.
      Product Information
      FormLyophilized
      Hill FormulaC₂₄H₂₇F₃N₄O₈
      Chemical formulaC₂₄H₂₇F₃N₄O₈
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Emission max.
      Excitation max.
      Peptide SequenceAc-VAD-AFC
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Caspase Substrate I, Fluorogenic Certificates of Analysis

      TitleLot Number
      218721

      References

      Hivatkozások áttekintése
      Susin, S.A., et al. 1999. J. Exp. Med. 189, 381.
      Thornberry, N.A. and Lazebnik, Y. 1998. Science 281, 1312.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-June-2008 RFH
      SynonymsAc-VAD-AFC
      DescriptionFluorogenic caspase-1 substrate. May also be used as a caspase-3, caspase-4, or caspase-7 substrate. Reaction can be monitored by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore. Excitation: ~400 nm; emission: ~505 nm.
      FormLyophilized
      Chemical formulaC₂₄H₂₇F₃N₄O₈
      Peptide SequenceAc-VAD-AFC
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage -20°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesSusin, S.A., et al. 1999. J. Exp. Med. 189, 381.
      Thornberry, N.A. and Lazebnik, Y. 1998. Science 281, 1312.