208292 L-Type Calcium Channel Blocker

208292
  
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      Áttekintés

      Replacement Information

      Kulcsspecifikációk táblázata

      Empirical FormulaCAS #
      C₁₄H₁₉ClN₂O₂S 387350-81-4
      Description
      Overview

      This product has been discontinued.





      A cell-permeable sulfonamide compound that reversibly interacts with the benzothiazepine-binding site and acts as a cardiac tissue selective L-type voltage gated Ca2+-channel activity inhibitor. Shown to display negative chronotropic activity with minimal vasorelaxation.
      Catalogue Number208292
      Brand Family Calbiochem®
      Synonyms(N-Cyclopropyl-N-piperidin-4-yl)-4-chlorobenzenesulfonamide
      References
      ReferencesCarosati, E., et al. 2006. J. Med. Chem. 49, 5206.
      Product Information
      CAS number387350-81-4
      ATP CompetitiveN
      FormWhite solid
      Hill FormulaC₁₄H₁₉ClN₂O₂S
      Chemical formulaC₁₄H₁₉ClN₂O₂S
      ReversibleY
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary TargetCardiac tissue selective L-type voltage gated Ca2+-channel activity inhibitor
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Irritant
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      L-Type Calcium Channel Blocker Certificates of Analysis

      TitleLot Number
      208292

      References

      Hivatkozások áttekintése
      Carosati, E., et al. 2006. J. Med. Chem. 49, 5206.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision05-April-2011 RFH
      Synonyms(N-Cyclopropyl-N-piperidin-4-yl)-4-chlorobenzenesulfonamide
      DescriptionA cell-permeable sulfonamide compound that reversibly interacts with the benzothiazepine-binding site and acts as a cardiac tissue selective L-type voltage gated Ca2+-channel activity inhibitor. Shown to display negative chronotropic activity with minimal vasorelaxation.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number387350-81-4
      Chemical formulaC₁₄H₁₉ClN₂O₂S
      Structure formulaStructure formula
      Purity≥95% by HPLC
      SolubilityDMSO (10 mg/ml)
      Storage +2°C to +8°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Irritant
      ReferencesCarosati, E., et al. 2006. J. Med. Chem. 49, 5206.