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505897 (±)-PD 128907 Hydrochloride - CAS 112960-16-4 - Calbiochem

(±)-PD 128907 Hydrochloride - CAS 112960-16-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Dopamine D₃ Receptor Agonist, PD 128,907, PD 128907, PD128907

Primary Target: D₃
505897
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      112960-16-4C₁₄H₁₉NO₃•HCl
      Description
      Overview

      This product has been discontinued.



      Selective dopamine D3 receptor agonist (Ki = 2.3 nM) with an 18-fold selectivity over long dopamine receptors (D2L) and exhibited only weak affinity for D4.2 receptors (Ki = 169 nM). Commonly used to reproduce cocaine′s discriminative stimulus effects and also in peripheral systemic studies of hypertension.
      Catalogue Number505897
      Brand Family Calbiochem®
      SynonymsDopamine D₃ Receptor Agonist, PD 128,907, PD 128907, PD128907
      References
      ReferencesAchat-Mendes, c. et al. 2010. J. Pharmacol. Exp. Ther. 334, 556.
      Zeng, C. et al. 2006. Circul. Res. 99, 494.
      Pugsley, T. A. et al. 1995. J. Pharmacol. Exp. Ther. 275, 1355.
      Product Information
      CAS number112960-16-4
      FormWhite powder
      Hill FormulaC₁₄H₁₉NO₃•HCl
      Chemical formulaC₁₄H₁₉NO₃•HCl
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetD₃
      Primary Target K<sub>i</sub>2.3 nM
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      505897 0

      Documentation

      (±)-PD 128907 Hydrochloride - CAS 112960-16-4 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Achat-Mendes, c. et al. 2010. J. Pharmacol. Exp. Ther. 334, 556.
      Zeng, C. et al. 2006. Circul. Res. 99, 494.
      Pugsley, T. A. et al. 1995. J. Pharmacol. Exp. Ther. 275, 1355.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-September-2013 JSW
      SynonymsDopamine D₃ Receptor Agonist, PD 128,907, PD 128907, PD128907
      DescriptionSelective dopamine D3 receptor agonist (Ki = 2.3 nM) with an 18-fold selectivity over long dopamine receptors (D2L) and exhibited only weak affinity for D4.2 receptors (Ki = 169 nM). Commonly used to reproduce cocaine′s discriminative stimulus effects and also in peripheral systemic studies of hypertension.
      FormWhite powder
      CAS number112960-16-4
      Chemical formulaC₁₄H₁₉NO₃•HCl
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (5 mg/ml)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesAchat-Mendes, c. et al. 2010. J. Pharmacol. Exp. Ther. 334, 556.
      Zeng, C. et al. 2006. Circul. Res. 99, 494.
      Pugsley, T. A. et al. 1995. J. Pharmacol. Exp. Ther. 275, 1355.