Millipore Sigma Vibrant Logo

189250 ATBI, Synthetic

ATBI, Synthetic MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Alkalo-thermophilic Bacillus Inhibitor, AGKKDDDDPPE

189250
  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Overview

      Replacement Information
      Description
      OverviewAn 11-residue hydrophilic peptide that acts as a potent inhibitor of aspartyl proteases. Inhibits pepsin in a slow-tight binding, competitive manner (Ki = 55 pM). Also functions as a tight binding, noncompetitive inhibitor of HIV-1 protease at the active site of the flap region (Ki = 17.8 nM). Also exhibits anti-fungal activity in Aspergillus, Fusarium, and Trichoderma species.
      Catalogue Number189250
      Brand Family Calbiochem®
      SynonymsAlkalo-thermophilic Bacillus Inhibitor, AGKKDDDDPPE
      References
      ReferencesDash, C., et al. 2001. Antimicrob. Agents Chemother. 45, 2008. Dash, C., et al. 2001. Biochemistry 40, 11525. Dash, C., and Rao, M. 2001. J. Biol. Chem. 276, 2487.
      Product Information
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₄₈H₇₅N₁₃O₂₂
      Chemical formulaC₄₈H₇₅N₁₃O₂₂
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Primary Targetpepsin
      Primary Target K<sub>i</sub>55 pM
      Secondary targetHIV protease (IC₅₀ = 17.8 nM)
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide SequenceH-Ala-Gly-Lys-Lys-Asp-Asp-Asp-Asp-Pro-Pro-Glu-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      189250 0

      Documentation

      ATBI, Synthetic Certificates of Analysis

      TitleLot Number
      189250

      References

      Reference overview
      Dash, C., et al. 2001. Antimicrob. Agents Chemother. 45, 2008. Dash, C., et al. 2001. Biochemistry 40, 11525. Dash, C., and Rao, M. 2001. J. Biol. Chem. 276, 2487.