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Buffer Detection Kit for Magnetic Beads
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233105
Sigma-AldrichCL-82198 - CAS 1188890-36-9 - Calbiochem
A selective inhibitor of MMP-13 (IC₅₀ = 10 µM).
More>>A selective inhibitor of MMP-13 (IC₅₀ = 10 µM). Less<<
CL-82198 - CAS 1188890-36-9 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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Description
Overview
A selective inhibitor of MMP-13 (IC50 = 10 µM). Binds to the S1′ pocket of MMP-13 with its morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE.
Catalogue Number
233105
Brand Family
Calbiochem®
References
References
Chen, J.M., et al. 2000. J. Am. Chem. Soc.122, 9648.
CL-82198 - CAS 1188890-36-9 - Calbiochem Certificates of Analysis
Title
Lot Number
233105
References
Reference overview
Chen, J.M., et al. 2000. J. Am. Chem. Soc.122, 9648.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
05-April-2011 RFH
Description
A selective inhibitor of MMP-13 (IC50 = 10 µM) that does not appear to act by chelating Zn2+. Binds within the entire S1' pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE.
Form
Light yellow solid
CAS number
1188890-36-9
Chemical formula
C₁₇H₂₂N₂O₃· HCl
Structure formula
Purity
≥97% by HPLC
Solubility
H₂O (25 mg/ml)
Storage
-20°C
Hygroscopic
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Chen, J.M., et al. 2000. J. Am. Chem. Soc.122, 9648.
