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504523 CP-101,606 - CAS 134234-12-1 - Calbiochem

CP-101,606 - CAS 134234-12-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Traxoprodil, CP-101606, (1S,2S)-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol, NMDA Antagonist VI

Primary Target: NMDA receptors
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      134234-12-1C₂₀H₂₅NO₃
      Description
      Overview

      This product has been discontinued.



      A highly selective antagonist for NR2B subunit containing NMDA receptors (IC50 = 0.039 µM for NR2B and >100 µM for NR2A, NR2C, and NR2D). Widely used as neuroprotective, analgesic, antidepressant, and anti-Parkinsonian agent in research.
      Catalogue Number504523
      Brand Family Calbiochem®
      SynonymsTraxoprodil, CP-101606, (1S,2S)-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol, NMDA Antagonist VI
      References
      ReferencesTaniguchi, K., et al. 2009. British J. Pharmacol. 122, 809.
      Menniti, F., et al. 1997. Eur. J. Pharmacol. 331, 117.
      Nicholson, K., et al. 2007. Behavioural Pharmacology 18, 731.
      Bullock, M., et al. 2006. Annals of the New York Academy of Sciences 890, 51.
      Preskorn, S., et al. 2008. J. Clin. Psychopharmacol. 28, 631.
      Yurkewicz, L., et al. 2005. J. Neurotrauma. 22, 1428.
      Product Information
      CAS number134234-12-1
      FormWhite powder
      Hill FormulaC₂₀H₂₅NO₃
      Chemical formulaC₂₀H₂₅NO₃
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetNMDA receptors
      Primary Target IC<sub>50</sub>0.039 µM for NR2B and >100 µM for NR2A, NR2C, and NR2D
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      504523 0

      Documentation

      CP-101,606 - CAS 134234-12-1 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Taniguchi, K., et al. 2009. British J. Pharmacol. 122, 809.
      Menniti, F., et al. 1997. Eur. J. Pharmacol. 331, 117.
      Nicholson, K., et al. 2007. Behavioural Pharmacology 18, 731.
      Bullock, M., et al. 2006. Annals of the New York Academy of Sciences 890, 51.
      Preskorn, S., et al. 2008. J. Clin. Psychopharmacol. 28, 631.
      Yurkewicz, L., et al. 2005. J. Neurotrauma. 22, 1428.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-June-2013 JSW
      SynonymsTraxoprodil, CP-101606, (1S,2S)-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenylpiperidino)-1-propanol, NMDA Antagonist VI
      DescriptionA highly selective antagonist for NR2B subunit containing NMDA receptors (IC50 = 0.039 µM for NR2B and >100 µM for NR2A, NR2C, and NR2D). Widely used as neuroprotective, analgesic, antidepressant, and anti-Parkinsonian agent in research.
      FormWhite powder
      CAS number134234-12-1
      Chemical formulaC₂₀H₂₅NO₃
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (35 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesTaniguchi, K., et al. 2009. British J. Pharmacol. 122, 809.
      Menniti, F., et al. 1997. Eur. J. Pharmacol. 331, 117.
      Nicholson, K., et al. 2007. Behavioural Pharmacology 18, 731.
      Bullock, M., et al. 2006. Annals of the New York Academy of Sciences 890, 51.
      Preskorn, S., et al. 2008. J. Clin. Psychopharmacol. 28, 631.
      Yurkewicz, L., et al. 2005. J. Neurotrauma. 22, 1428.