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05-23-1701 FR-1

FR-1 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: CRGDSPASSC, Cyclic

Primary Target: ADP-induced platelet aggregation
05-23-1701
  
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      Overview

      Replacement Information

      Key Spec Table

      Empirical Formula
      C₃₅H₅₇N₁₃O₁₆S₂
      Description
      Overview

      This product has been discontinued.





      A cyclic peptide containing the cell binding domain Arg-Gly-Asp and the associated cell migration sequence Pro-Ala-Ser-Ser of fibronectin. A potent inhibitor of ADP-induced platelet aggregation (IC50 = 7.6 µM).
      Catalogue Number05-23-1701
      Brand Family Calbiochem®
      SynonymsCRGDSPASSC, Cyclic
      References
      ReferencesKatow, H., et al. 1997. Dev. Growth Differ. 39, 207.
      Yamamoto, Y., et al. 1995. Chem. Lett. 11.
      Product Information
      FormWhite to off-white lyophilized solid
      Hill FormulaC₃₅H₅₇N₁₃O₁₆S₂
      Chemical formulaC₃₅H₅₇N₁₃O₁₆S₂
      Hygroscopic Hygroscopic
      Sold on the basis of peptide contentY
      Applications
      Biological Information
      Primary TargetADP-induced platelet aggregation
      Primary Target IC<sub>50</sub>7.6 µM
      Purity≥97% by HPLC
      Physicochemical Information
      Peptide ContentY
      Peptide SequenceH-Cys¹-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Cys¹⁰-OH (disulfide bond: 1 → 10)
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      05-23-1701 0

      Documentation

      FR-1 Certificates of Analysis

      TitleLot Number
      05-23-1701

      References

      Reference overview
      Katow, H., et al. 1997. Dev. Growth Differ. 39, 207.
      Yamamoto, Y., et al. 1995. Chem. Lett. 11.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision18-September-2008 RFH
      SynonymsCRGDSPASSC, Cyclic
      DescriptionA cyclic peptide containing the cell binding domain Arg-Gly-Asp and associated cell migration Pro-Ala-Ser-Ser sequences of fibronectin. A potent inhibitor of ADP-induced platelet aggregation (IC50 = 7.6 µM).
      FormWhite to off-white lyophilized solid
      Chemical formulaC₃₅H₅₇N₁₃O₁₆S₂
      Peptide SequenceH-Cys¹-Arg-Gly-Asp-Ser-Pro-Ala-Ser-Ser-Cys¹⁰-OH (disulfide bond: 1 → 10)
      Purity≥97% by HPLC
      Solubility5% Acetic acid (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      ReferencesKatow, H., et al. 1997. Dev. Growth Differ. 39, 207.
      Yamamoto, Y., et al. 1995. Chem. Lett. 11.