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108219 Tris(hidroksimetil)aminometana hidroklorida

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Tris(hidroksimetil)aminometana hidroklorida MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer

CAS #: 1185-53-1 EC Number: 214-684-5 Molar Mass: 157.60 g/mol Chemical Formula: C₄H₁₁NO₃*ClH Hill Formula: C₄H₁₁NO₃˙ ClH
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108219
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Overview

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Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar Mass
1185-53-1214-684-5C₄H₁₁NO₃˙ ClHC₄H₁₁NO₃*ClH157.60 g/mol

Pricing & Availability

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      		 Peti/Kotak fiber 3 x 0,750 kg
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      1082195000
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          		 Botol plastik 5 kg
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              		 Drum plastik 10 kg
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              1082199012
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                  		 Ember plastik 12 kg
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                  1082199050
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                      		 Drum plastik 50 kg
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                      Description
                      Catalogue Number108219
                      SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
                      DescriptionTris(hydroxymethyl)aminomethane hydrochloride
                      References
                      Product Information
                      CAS number1185-53-1
                      EC number214-684-5
                      Hill FormulaC₄H₁₁NO₃˙ ClH
                      Chemical formulaC₄H₁₁NO₃*ClH
                      Molar Mass157.60 g/mol
                      HS Code2922 19 00
                      Structure formula ImageStructure formula Image
                      Quality LevelMQ500
                      Applications
                      Biological Information
                      Physicochemical Information
                      Density1.28 g/cm3 (20.2 °C)
                      Melting Point150.7 °C
                      pH value4.2 (100 g/l, H₂O, 20 °C)
                      Vapor pressure<0.1 hPa (50 °C)
                      Solubility561 g/l larut
                      Dimensions
                      Materials Information
                      Toxicological Information
                      Safety Information according to GHS
                      Storage class10 - 13 Cairan dan padatan lain
                      WGKWGK 1 agak berbahaya untuk air
                      Disposal3
                      Reagen organik yang relatif tidak aktif harus dikumpulkan dalam kategori A. Jika terhalogenasi, harus ditempatkan dalam Kategori B. Untuk residu padat gunakan Kategori C.
                      Safety Information
                      Product Usage Statements
                      Storage and Shipping Information
                      StorageSimpan pada +15°C hingga +25°C.
                      Packaging Information
                      Transport Information
                      Supplemental Information
                      Specifications
                      Appearancewhite to almost white, crystalline powder
                      Assay (alkalimetric, calculated on dried substance)≥ 99.0 %
                      Identity (IR-spectrum)conforms
                      pH-value (0.5 mol/l, water)3.5 - 5.0
                      Melting point147 - 153 °C
                      UV-Absorption (230 nm; 10 %; 1 cm; water)≤ 0.1
                      UV-Absorption (260 nm; 10 %, 1 cm; water)≤ 0.06
                      UV-Absorption (280 nm; 10 %; 1 cm; water)≤ 0.06
                      UV-Absorption (300 nm; 10 %; 1 cm; water)≤ 0.02
                      UV-Absorption (400 nm; 10 %; 1 cm; water)≤ 0.01
                      Residual solvents (ICHQ3C) of class 2 (Methanol)≤ 3000 ppm
                      Residual solvents (ICHQ3C) of class 2 (Nitromethane)≤ 50 ppm
                      Residual solvents (ICHQ3C) of class 3 (Ethanol)≤ 5000 ppm
                      Residual solvents (ICHQ3C) of class 3 (Ethylmethylketon)≤ 5000 ppm
                      Other residual solvents (ICH Q3C)excluded by manufacturing process
                      Sulfated ash≤ 0.03
                      Loss on Drying (105°C)≤ 0.5
                      Endotoxins< 2.5
                      Total aerobic microbial count≤ 10²
                      Total yeast and mould count
                      ≤ 10²
                      Salmonella spp.
                      absent in 10 g
                      E.coli
                      absent in 1 g
                      Staphylococcus aureus
                      absent in 1 g
                      Pseudomonas aeruginosa
                      absent in 1 g
                      Candida albicans
                      absent in 1 g
                      Bile tolerante gram negative bacteria
                      absent in 1 g
                      DNases (Exo- and endonucleases)
                      not detected
                      Proteases
                      not detected
                      RNases
                      not detected
                      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
                      Total yeast and mould count
                      ≤ 10²
                      Salmonella spp.
                      absent in 10 g
                      E.coli
                      absent in 1 g
                      Staphylococcus aureus
                      absent in 1 g
                      Pseudomonas aeruginosa
                      absent in 1 g
                      Candida albicans
                      absent in 1 g
                      Bile tolerante gram negative bacteria
                      absent in 1 g
                      DNases (Exo- and endonucleases)
                      not detected
                      Proteases
                      not detected
                      RNases
                      not detected
                      Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
                      Global Trade Item Number
                      Catalogue Number GTIN
                      1082190003 04027269296049
                      1082195000 04022536532899
                      1082199010 04022536702742
                      1082199012 04027269285586
                      1082199050 04054839392443

                      Documentation

                      Material Qualification Dossier

                      TitleVersion
                      7.0

                      Quality Management Dossier (Open Access)

                      Title

                      Operational Excellence Dossier

                      Title

                      Tris(hidroksimetil)aminometana hidroklorida MSDS

                      Title

                      Safety Data Sheet (SDS) 

                      Tris(hidroksimetil)aminometana hidroklorida Certificates of Analysis

                      Product Number PackagingSpecificationLot Number
                      1082190003 Peti/Kotak fiberPDF Specification Document
                      1082195000 Botol plastikPDF Specification Document
                      1082199010 Drum plastikPDF Specification Document
                      1082199012 Ember plastikPDF Specification Document
                      1082199050 Drum plastikPDF Specification Document

                      Certificates

                      Title