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506135 Venlafaxine Hydrochloride - CAS 99300-78-4 - Calbiochem

Venlafaxine Hydrochloride - CAS 99300-78-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: SERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien

Primary Target: SERT/NET
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      99300-78-4C₁₇H₂₇NO₂·HCl
      Description
      OverviewA dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.
      Catalogue Number506135
      Brand Family Calbiochem®
      SynonymsSERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien
      References
      ReferencesKaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci. 2, 22.
      Aboelwafa, A., et al. 2010. AAPS PharmSciTech. 11, 1026.
      Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry. 97, 729.
      Product Information
      CAS number99300-78-4
      FormWhite solid
      Hill FormulaC₁₇H₂₇NO₂·HCl
      Chemical formulaC₁₇H₂₇NO₂·HCl
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetSERT/NET
      Primary Target K<sub>i</sub>82 nM
      Purity≥99% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      506135 0

      Documentation

      Venlafaxine Hydrochloride - CAS 99300-78-4 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Kaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci. 2, 22.
      Aboelwafa, A., et al. 2010. AAPS PharmSciTech. 11, 1026.
      Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry. 97, 729.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-November-2013 JSW
      SynonymsSERT/NET Inhibitor, Venlafaxine, Serotonin-norepinephrine Inhibitor, Venlafaxien
      DescriptionA dual reuptake inhibitor of serotonin-norepinephrine with strong preference to serotonin (Ki = 82 and 2480 nM for SERT and NET respectively). Also inhibits reuptake of dopamine. Used in studies of depression, ADHD, and stress-related anxiety.
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number99300-78-4
      Chemical formulaC₁₇H₂₇NO₂·HCl
      Structure formulaStructure formula
      Purity≥99% by HPLC
      SolubilityDMSO (50 mM) or H₂O (100 mM)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesKaur, J., et al. et al. 2010. J. Pharmacy & Bioallied Sci. 2, 22.
      Aboelwafa, A., et al. 2010. AAPS PharmSciTech. 11, 1026.
      Bernardi, S., et al. 2009. J. Thermal Analysis & Calorimetry. 97, 729.