Recombinant, human bone morphogenetic protein-4 (BMP-4) expressed in E. coli and purified by proprietary chromatographic methods. BMP-4 is a monomeric protein that belongs to the transforming growth factor-β (TGF-β) superfamily. BMP-4 plays an important role in the development of various organs. It is essential for bone growth and regeneration in periodontal tissue.
Catalogue Number
203642
Brand Family
Calbiochem®
Synonyms
Bone morphogenetic protein 4 precursor, BMP-2B
References
References
Giacomini, D., et al. 2006. Endocrinology147, 247. Hsieh, P.C., et al. 2006. J. Vasc. Surg.43, 150. Kuroda, R., et al. 2006. Arthritis Rheum.54, 433. Frank, D., et al. 2005. Chest128, 590S. Han, D.K., et al. 2005. J. Periodontol.76, 2216. Klosch, B., et al. 2005. Biotechnol. Lett.27, 1559.
Endotoxin:< 0.1 ng/µg of Bone Morphogenetic Protein-4
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code
Blue Ice Only
Toxicity
Standard Handling
Storage
-20°C
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for 2-7 days at 4°C or for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Documentation
BMP-4, Human, Recombinant, E. coli Certificates of Analysis
Title
Lot Number
203642
References
Reference overview
Giacomini, D., et al. 2006. Endocrinology147, 247. Hsieh, P.C., et al. 2006. J. Vasc. Surg.43, 150. Kuroda, R., et al. 2006. Arthritis Rheum.54, 433. Frank, D., et al. 2005. Chest128, 590S. Han, D.K., et al. 2005. J. Periodontol.76, 2216. Klosch, B., et al. 2005. Biotechnol. Lett.27, 1559.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
Revision
20-May-2008 RFH
Synonyms
Bone morphogenetic protein 4 precursor, BMP-2B
Description
Recombinant, human bone morphogenetic protein-4 (BMP-4) expressed in E. coli and purified by proprietary chromatographic methods. BMP-4 is a monomeric protein that belongs to the transforming growth factor-β (TGF-β) superfamily. BMP-4 plays an important role in the development of various organs. It is essential for bone growth and regeneration in periodontal tissue.
Form
Lyophilized
Purity
≥95% by SDS-PAGE
Contaminants
Endotoxin:< 0.1 ng/µg of Bone Morphogenetic Protein-4
Solubility
Reconstitute to ≥100 µg/ml in sterile H₂O containing 0.1% HSA or BSA. Further dilutions can be made with aqueous buffers just prior to use.
Storage
-20°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for 2-7 days at 4°C or for up to 6 months at -20°C.
Toxicity
Standard Handling
References
Giacomini, D., et al. 2006. Endocrinology147, 247. Hsieh, P.C., et al. 2006. J. Vasc. Surg.43, 150. Kuroda, R., et al. 2006. Arthritis Rheum.54, 433. Frank, D., et al. 2005. Chest128, 590S. Han, D.K., et al. 2005. J. Periodontol.76, 2216. Klosch, B., et al. 2005. Biotechnol. Lett.27, 1559.
