Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on More

106432 tri-Sodium citrate dihydrate


Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar MassGrade Value
6132-04-3200-675-3C₆H₅Na₃O₇ * 2 H₂O294.10 g/molPh Eur,BP,JP,USP,E 331


Catalogue NumberPackaging Qty/Pack
1064321000 Plastic bottle 1 kg
1064325000 Plastic bottle 5 kg
1064329029 Double PE Sack 25 kg
1064329052 Plastic drum 50 kg
Catalogue Number106432
SynonymsTrisodium Citrate, Sodium Citrate, Dihydrate
Product Information
CAS number6132-04-3
EC number200-675-3
GradePh Eur,BP,JP,USP,E 331
Hill FormulaC₆H₅Na₃O₇ * 2 H₂O
Molar Mass294.10 g/mol
HS Code2918 15 00
Structure formula ImageStructure formula Image
Quality LevelMQ500
Biological Information
Physicochemical Information
Melting Point300 °C (anhydrous substance)
pH value7.5 - 9.0 (50 g/l, H₂O, 25 °C)
Bulk density600 kg/m3
Solubility720 g/l
Materials Information
Toxicological Information
LD 50 oralLD50 Rat > 8000 mg/kg
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Assay (Perchloric acid titration, calc. on anhydrous substance (Ph Eur))99.0 - 101.0 %
Assay (Perchloric acid titration, previously dried substance) (JP/USP)99.0 - 100.5 %
Identity (Na)passes test
Identity (Citrate)passes test
Identity (reaction upon ignition)passes test
Appearancewhite to almost white crystals
Appearance of solution (100 g/l, CO₂-free water)clear and colorless
Acidity or alkalinitypasses test
pH (50 g/l CO₂-free water)7.5 - 8.5
Chloride (Cl)≤ 50 ppm
Sulfate (SO₄)≤ 150 ppm
Al (Aluminium)≤ 5 ppm
As (Arsenic)≤ 1 ppm
Hg (Mercury)≤ 1 ppm
Pb (Lead)≤ 1 ppm
Oxalate (as C₂H₂O₄)≤ 100 ppm
Tartrate (C₄H₄O₆)passes test
Residual solvents (ICH (Q3C))excluded by manufacturing process
Readily carbonisable substancepasses test
Water (according to Karl Fischer)11.0 - 13.0 %
Loss on drying (180 °C, 18 h)10.0 - 13.0 %
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, JP, USP, E 331
Conforms to the purity criteria on food additives according to the current European Commission Regulation.
Corresponds to Ph. Eur., BP, JP, USP, E 331
Conforms to the purity criteria on food additives according to the current European Commission Regulation.
Global Trade Item Number
Catalogue Number GTIN
1064321000 04022536076621
1064325000 04022536076645
1064329029 04022536940090
1064329052 04027269971052


Material Qualification Dossier


Quality Management Dossier (Open Access)


Operational Excellence Dossier


tri-Sodium citrate dihydrate SDS


Safety Data Sheet (SDS) 

tri-Sodium citrate dihydrate Certificates of Analysis

Product Number PackagingSpecificationLot Number
1064321000 Plastic bottlePDF Specification Document
1064325000 Plastic bottlePDF Specification Document
1064329029 Double PE SackPDF Specification Document
1064329052 Plastic drumPDF Specification Document