Columns for USP Specifications
Columns for USP Specifications |
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Merck offers a comprehensive range of high-quality HPLC columns. Among these are a wide selection of columns that meet USP (United States Pharmacopoeia) specifications. The L nomenclature was introduced by the USP to designate column types for high-performance liquid chromatography. To help you select the appropriate HPLC column for your application, the table below describes various L columns as well as the corresponding HPLC columns available from Merck.
USP |
Description |
Columns |
|---|---|---|
| L1 | Octadecly silane (ODS or C18) chemically bonded to porous silica or ceramic particles, 1.5 to 10 µm in diameter | Chromolith® RP-18 Endcapped LiChrosorb® RP-18 (5 µm) LiChrosorb® RP-18 (10 µm) LiChrospher® RP-18 (5 µm) LiChrospher® RP-18 (10 µm) LiChrospher® RP-18 Endcapped (5 µm) LiChrospher® RP-18 Endcapped (10 µm) Purospher® RP-18 (5 µm) Purospher® RP-18 Endcapped (5 µm) Purospher® STAR RP-18 Endcapped (3 µm) Purospher® STAR RP-18 Endcapped (5 µm) Superspher® RP-18 Endcapped (4 µm) Superspher® RP-18 (4 µm) |
| L3 | Porous silica particles, 1.5 to 10 µm in diameter | Chromolith® Si LiChrosorb® Si 60 (5 µm) LiChrospher® Si 100 LiChrospher® Si 60 (10 µm) LiChrospher® Si 60 (5 µm) Purospher® STAR Si (5 µm) Superspher® Si 60 (4 µm) |
| L7 | Octyl silane (C8) chemically bonded to porous silica particles, 1.5 to 10 µm in diameter | Chromolith® RP-8 Endcapped LiChrosorb® RP-8 (5 µm) LiChrosorb® RP-8 (10 µm) LiChrospher® RP-8 (5 µm) LiChrospher® RP-8 (10 µm) LiChrospher® RP-8 endcapped (5 µm) LiChrospher® RP-Select B (5 µm) LiChrospher® RP-Select B (10 µm) Purospher® STAR RP-8 Endcapped (3 µm) Purospher® STAR RP-8 Endcapped (5 µm) Superspher® 60 RP-8 (4 µm) Superspher® 60 RP-8 Endcapped (4 µm) Superspher® 60 RP-Select B (4 µm) |
| L8 | An essentially monomolecular layer of aminopropylsilane (NH2) chemically bonded to totally porous silica gel support, 3 to 10 µm in diameter | LiChrospher® NH2 (10 µm) Purospher® STAR NH2 (5 µm) |
| L10 | Nitrile groups (CN) chemically bonded to porous silica particles, 3 to 10 µm in diameter | LiChrospher® CN (10 µm) LiChrospher® CN (5 µm) |
| L20 | Dihydroxypropane groups chemically bonded to porous silica particles, 3 to 10 µm in diameter | LiChrospher® Diol (5 µm) LiChrosorb® Diol (5 µm) |
| L29 | Gamma alumina, reversed-phase, low carbon percentage by weight alumina-based polybutadiene spherical particles, 5 µm in diameter with a pore diameter of 80Å | Aluspher® RP-select B |
| L45 | Beta cyclodextrin bonded to porous silica particles, 5 to 10 µm in diameter | ChiraDex® (5 µm) |
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