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HomeWebinarsCan Nuclear Genotyping Advance the World of Chemical Standards?

Can Nuclear Genotyping Advance the World of Chemical Standards?

Webinar

The distinction of nuclear magnetic resonance (NMR) as a metrologically validated, relative primary analytical method has given quantitative NMR (qNMR) a unique stature in the world of reference standards. Parallel to this development, the fundamental physical principles underlying (q)NMR have recently been matched with previously unavailable computational power for the analysis of NMR spectra. Collectively, this had led to the development of unprecedented capabilities that transform the classical visual (“phenotypic”) interpretation of NMR spectra into a next-generation process that permits the genotypic profiling of molecules.

  • Understand how recent computational advances empower analysis of NMR spectra for genotypic profiling of molecules.
  • Explore the link between fundamental science, metrology, and practical applications for chemical and pharmaceutical reference standards.
  • Learn to interpret NMR spectra beyond traditional phenotypic views, leveraging genotypic information to enhance standardization and quality control.

Speakers

Guido F. Pauli, Dr. rer. nat., FAPA

Guido F. Pauli, Dr. rer. nat., FAPA

UIC Retzky College of Pharmacy, University of Illinois Chicago, Chicago (IL)

Professor and Director

A pharmacist specialized in pharmaceutical analysis with a doctoral degree in natural products, his basic and translational research involves drug discovery, complex natural health products, and pharmaceutical analysis. He develops analytical and NP technologies such as quantitative NMR spectroscopy and countercurrent separation, applied to clinical interventions, anti-TB antibiotics, dental materials, and innovation of drug discovery workflows. His expertise international panel efforts aim at advancing pharmaceutical QC, complementary therapies, training the next generation of scientists. His academic track record includes mentorship of 80+ Ph.D. students, postdocs, and visiting scientists, active global collaborations, and 300+ publications, associated with Scopus/Google h-indices of 67/79.