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Merck

H2904

HistoChoice® Tissue Fixative

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About This Item

NACRES:
NA.47
UNSPSC Code:
12352202
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color

colorless

Quality Level

application(s)

hematology
histology

storage temp.

room temp

Application

Designed for the molecular biologist. Specially formulated to preserve antigenic sites for antibody probes and nucleic acid sites for in situ hybridizations. Fixed sections do not require predigestion or other recovery procedures to make important sites available.

Analysis Note

Contains no formaldehyde, glutaraldehyde or mercury. Non-toxic

Legal Information

HistoChoice is a registered trademark of Amresco, Inc.


signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 2 - Muta. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 1

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter



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Three-dimensional (3D) printing of biological tissue is rapidly becoming an integral part of tissue engineering.


D G Vince et al.
Analytical cellular pathology : the journal of the European Society for Analytical Cellular Pathology, 15(2), 119-129 (1997-01-01)
Formaldehyde fixatives have traditionally been used to preserve tissues as they impart excellent morphological preservation. Formaldehyde fixes tissue by cross linking, a process which can reduce the antigenicity of tissue and weakens the intensity of immunohistochemical stains. Preliminary studies have
M A Kacena et al.
Biotechnic & histochemistry : official publication of the Biological Stain Commission, 79(5-6), 185-190 (2005-03-15)
We compared histochemical and immunohistochemical staining as well as fluorochrome labeling in murine bone specimens that were fixed with 10% neutral buffered formalin to those fixed with HistoChoice. We showed that sections from undecalcified tibiae fixed for 4 h in
Erik P Rader et al.
Aging cell, 17(5), e12816-e12816 (2018-07-12)
Snell dwarf mice (Pit1dw/dw ) exhibit deficiencies in growth hormone, prolactin, and thyroid stimulating hormone. Besides being an experimental model of hypopituitarism, these mice are long-lived (>40% lifespan extension) and utilized as a model of slowed/delayed aging. Whether this longevity