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Merck

14-607-M

PIM2 Protein, active, 25 µg

Active, human PIM2 expressed in E. coli, purified using GSH agarose, for use in Kinase Assays.

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
eCl@ss:
32160405

Product Name

PIM2 Protein, active, 25 µg, Active, human PIM2 expressed in E. coli, purified using GSH agarose, for use in Kinase Assays.

biological source

human

mol wt

Mw 63.4 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

UniProt accession no.

Quality Level

Gene Information

human ... PIM2(11040)

Analysis Note

routinely evaluated by phosphorylation of PIM2tide

General description

Product Source: N-terminal GST-tagged recombinant full-length human PIM2
human PIM2 expressed in E. coli, purified using GSH agarose

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Physical form

GSH agarose

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Casey J Fox et al.
Genes & development, 17(15), 1841-1854 (2003-07-19)
Growth factor withdrawal results in the termination of factor-dependent transcription. One transcript that declines rapidly following growth factor deprivation of hematopoietic cells is the serine/threonine kinase pim-2. When constitutively expressed, Pim-2 conferred long-term resistance to a variety of apoptotic stimuli
Bin Yan et al.
The Journal of biological chemistry, 278(46), 45358-45367 (2003-09-05)
Hematopoietic growth factors mediate the survival and proliferation of blood-forming cells, but the mechanisms through which these proteins produce their effects are incompletely known. Recent studies have identified the pim family of kinases as mediators of cytokine-dependent survival signals. Several

Global Trade Item Number

SKUGTIN
14-607M04053252411762
14-60704053252510861

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