14-746-M
Src (1-530) Protein, active, 10 µg
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About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
eCl@ss:
32160405
UniProt accession no.
Quality Level
Gene Information
human ... SRC(6714)
biological source
human
mol wt
Mw 61.7 kDa
manufacturer/tradename
Upstate®
technique(s)
activity assay: suitable (kinase)
GenBank accession no.
Application
Active, N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells. For use in Kinase Assays.
Research Category
Metabolism
Metabolism
Research Sub Category
Cardiovascular Disease
Metabolic Disorders
Cardiovascular Disease
Metabolic Disorders
Biochem/physiol Actions
Protein Target: Src
Target Sub-Family: TK
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
N-terminal 6His-tagged, recombinant, human Src, amino acids 1-530, expressed by baculovirus in Sf21 insect cells.
Product Source: Expressed by baculovirus in Sf21 insect cells.
The mutant form of Src (Src, 1-530) has been identified in cases of advanced colon cancer. This truncating mutation generates an open active form of Src that has been found to be transforming, tumorigenic and metastasis promoting.
Other Notes
For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Packaging
Also available in 250μg size as catalog # 14-746M - Call for pricing and availability.
Physical form
50mM Tris-HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol. Frozen solution
Ni2+/NTA-agarose
Preparation Note
6 months at -70°C from date of shipment.
Legal Information
GenBank is a registered trademark of United States Department of Health and Human Services
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 14-746 | 04053252741845 |
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