14-938-M
TLK1
Synonym(s):
PKU-beta, Serine/threonine-protein kinase tousled-like 1, Tousled-like kinase 1
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About This Item
UNSPSC Code:
12352202
eCl@ss:
32160405
General description
This protein is a serine/threonine kinase that may be involved in the regulation of chromatin assembly. The protein is only active when it is phosphorylated, and this phosphorylation is cell cycle-dependent, with the maximal activity of this protein coming during S phase. The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication. Three transcript variants encoding different isoforms have been found for this gene.
Analysis Note
Routinely evaluated by phosphorylation of casein
Other Notes
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Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
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