23-057-M
Smac/DIABLO
Synonym(s):
Diablo homolog, mitochondrial, Direct IAP-binding protein with low pI, Second mitochondria-derived activator of caspase (Smac)
Sign In to View Organizational & Contract Pricing.
Select a Size
All Photos(1)
About This Item
UNSPSC Code:
12352202
NACRES:
NA.32
eCl@ss:
32160405
General description
Smac/DIABLO is a mitochondrial protein that is proteolytically processed and released during apoptosis along with cytochrome c and other pro-apoptotic factors. Once in the cytosol, Smac/DIABLO binds to inhibitors of apoptosis (IAP) proteins and disrupts the ability of the IAPs to inhibit caspases 3, 7, and 9 thereby promoting apoptosis. Along with several other pro-apoptotic proteins, Smac/DIABLO has been shown to be a substrate for the ubiquitin ligase XIAP.
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Skin Sens. 1
Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 23-057M | 04053252919077 |
| 23-057 | 04053252919060 |
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service