524615
L-α-Phosphatidylinositol-3,4,5-trisphosphate, Dipalmitoyl-, Heptaammonium Salt - Calbiochem
Synonym(s):
PI-3,4,5-P₃, 7NH₄, PIP₃, Dipalmitoyl-
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About This Item
Assay
≥98% (NMR)
form
solid
color
white
solubility
DMSO: 1 mg/mL
General description
Activates Ca2+-insensitive PKC isozymes δ, ε, and η. Binds to the general receptor for phosphoinositide-1 (GRP1) protein through a plekstrin homology (PH) domain. Also reported to increase the motility of NIH/3T3 cells and produce actin reorganization and membrane ruffling.
Synthetic. Activates Ca2+-insensitive PKC isotypes δ, ε, and η. Binds to the GRP1 protein through a plekstrin homology (PH) domain. Also reported to increase the motility of NIH 3T3 cells and produce actin reorganization and membrane ruffling.
Biochem/physiol Actions
Ca2+-insensitive PKC isozymes Δ, ε, and η
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
Storage Class Code
10-13 - German Storage Class 10 to 13
Certificates of Analysis (COA)
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