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Merck

AB10340

Anti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A

serum, Chemicon®

Synonym(s):

ATP binding cassette transporter 1, ATP-binding cassette 1, ATP-binding cassette transporter 1, ATP-binding cassette, sub-family A (ABC1), member 1, ATP-binding cassette, sub-family A member 1, ATP-binding cassette, sub-family A, member 1, Cholesterol ef

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-ATP-binding cassette Antibody, sub-family B (MDR/TAP), member 1A, serum, Chemicon®

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse

species reactivity (predicted by homology)

rat

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_011076

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Immunogen

Epitope: AA N629 – W704
Recombinant

Physical form

Raw rabbit serum with 0.05% sodium azide.

Preparation Note

Maintain at -20°C for up to 12 months from date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Analysis Note

Routinely evaluated by Western Blot on baculovirus expressed recombinant ABC protein.

Application

Anti-ATP-binding cassette, sub-family B (MDR/TAP), member 1A detects levels of ATP-binding cassette proteins & has been published & validated for use in WB.
Research Category
Metabolism
Research Sub Category
Toxicology & Drug Resistance
Western Blot Analysis: A 1:5000 dilution of this lot detected baculovirus expressed recombinant ABC protein.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

141 kDa
This protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. There are seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The MDR/TAP subfamily are involved in multidrug resistance. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes, and celiac disease.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

Certificates of Analysis (COA)

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Adám Sike et al.
PloS one, 9(1), e84915-e84915 (2014-01-11)
The multidrug-resistant phenotype of tumor cells is acquired via an increased capability of drug efflux by ABC transporters and causes serious problems in cancer treatment. With the aim to uncover whether changes induced by epigenetic mechanisms in the expression level

Global Trade Item Number

SKUGTIN
AB1034004053252625886

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