AB10428

Anti-Kallikrein-3 (KLK3) (CT) Antibody

Name: Anti-Kallikrein-3 (KLK3) (CT) Antibody
Brand: MM

from rabbit

Synonym(s):

P-30 antigen, Kallikrein-3, kallikrein-related peptidase 3

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Product Name

Anti-Kallikrein-3 (KLK3) (CT) Antibody, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

saturated ammonium sulfate (SAS) precipitated

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat, human

technique(s)

western blot: suitable

NCBI accession no.

NP_001639

UniProt accession no.

P07288

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... KLK3(354)

Analysis Note

Control
Western Blot : Mouse brain lysate.

Western Blot Analysis: 1:250 dilution of this antibody detected KLK3 on mouse brain lysate.

Application

This Anti-Kallikrein-3 (KLK3) (C-term) Antibody is validated for use in WB for the detection of Kallikrein-3 (KLK3) (C-term).

Biochem/physiol Actions

Other species have not been tested.

The antibody reacts with the 29 kDa KLK3 antigen.

General description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein.

~31 kDa observed.
Band may migrate from the calculated 29 kDa to ~31 kDa on western blot.

Immunogen

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK3.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Saturated Ammonium Sulfate (SAS)

Preparation Note

Store at 2-8°C for 6 months from date of receipt. For long term storage, store at -20°

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Increased Klk9 Urinary Excretion Is Associated to Hypertension-Induced Cardiovascular Damage and Renal Alterations.

Ana M Blázquez-Medela et al.

Medicine, 94(41), e1617-e1617 (2015-10-16)

Early detection of hypertensive end-organ damage and secondary diseases are key determinants of cardiovascular prognosis in patients suffering from arterial hypertension. Presently, there are no biomarkers for the detection of hypertensive target organ damage, most outstandingly including blood vessels, the

Global Trade Item Number

SKU	GTIN
AB10428	04053252286025

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