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Merck

AB10526

Anti-COX4 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

cytochrome c oxidase subunit IV isoform 1, cytochrome c oxidase subunit IV1, Cytochrome c oxidase polypeptide IV, cytochrome c oxidase subunit 4 isoform 1, mitochondrial

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

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Product Name

Anti-COX4 Antibody, from rabbit, purified by affinity chromatography

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

packaging

antibody small pack of 25 μg

technique(s)

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI accession no.

NP_001852

UniProt accession no.

P13073

shipped in

ambient

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... COX4I1(1327)

Related Categories

Analysis Note

Control
Human fetal skeletal muscle tissue lysate
Evaluated by Western Blot in human fetal skeletal muscle tissue lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected COX4 in 10 µg of human fetal skeletal muscle tissue lysate.

Application

Anti-COX4 Antibody detects level of COX4 & has been published & validated for use in WB, IH(P).
Immunohistochemistry Analysis: A 1:500 dilution from a previous lot detected COX4 in normal human cardiac muscle tissue.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

Biochem/physiol Actions

Other homologies: Rat and mouse (59% sequence homology).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Cytochrome C oxidase subunit 4 (COX4), is one of 13 subunits of cytochrome c oxidase. Cytochrome c oxidase is responsible for catalyzing the last step of electron transfer through the respiratory chain on the mitochondrial inner membrane. COX4 assembles into sub-complexes with other subunits of cytochrome c oxidase and may represent a rate-limiting intermediate.
~17 kDa observed.
A non-specific band may be observed at ~58 kDa

Immunogen

KLH-conjugated linear peptide corresponding to human COX4.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

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Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
AB1052604053252645242
AB10526-25UG04054839342554

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