AB1921
Anti-Integrin alpha 5 (ITGA5/CD49E) Antibody
CHEMICON®, rabbit polyclonal
Synonym(s):
CD49e
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Product Name
Anti-Integrin α5 Antibody, serum, Chemicon®
biological source
rabbit
Quality Level
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... ITGA5(3678)
Immunogen
Recombinant fragment of mouse alpha5 integrin (Holers et al. 1989) corresponding to amino acid residues 655-880 of the human protein (Argraves 1987). This region of the molecule is extracellular and is included in the heavy chain (120 kDa).
Application
Detect Integrin α5 using this Anti-Integrin α5 Antibody validated for use in ELISA, WB, IH.
ELISA.
Western blotting: (The antigen should be separated in SDS-PAGE under reducing conditions
and does not react with non-reduced sample.): 1:5,000.
Immunohistochemistry/Immunofluorescence: 1:1,000.
Optimal working dilutions must be determined by the end user.
Western blotting: (The antigen should be separated in SDS-PAGE under reducing conditions
and does not react with non-reduced sample.): 1:5,000.
Immunohistochemistry/Immunofluorescence: 1:1,000.
Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Biochem/physiol Actions
Specific for alpha5 integrin as determined by Western blotting.
Physical form
Whole rabbit serum. Liquid, with 0.02% sodium azide.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Opposing effects of collagen I and vitronectin on fibronectin fibril structure and function.
Gildner, CD; Roy, DC; Farrar, CS; Hocking, DC
Matrix Biology null
Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeleton tension.
Coyer, SR; Singh, A; Dumbauld, DW; Calderwood, DA; Craig, SW; Delamarche, E; Garcia, AJ
Journal of Cell Science null
Sirika Pillay et al.
Journal of virology, 91(18) (2017-07-07)
Adeno-associated virus (AAV) entry is determined by its interactions with specific surface glycans and a proteinaceous receptor(s). Adeno-associated virus receptor (AAVR) (also named KIAA0319L) is an essential cellular receptor required for the transduction of vectors derived from multiple AAV serotypes
AMPA receptor stimulation increases alpha5beta1 integrin surface expression, adhesive function and signaling.
Lin, CY; Lynch, G; Gall, CM
Journal of Neurochemistry null
CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes.
Nishida, T; Kawaki, H; Baxter, RM; Deyoung, RA; Takigawa, M; Lyons, KM
Journal of Cell Communication and Signaling null
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB1921 | 04053252623608 |
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