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Key Documents

AB1968

Sigma-Aldrich

Anti-Integrin beta 3 (ITGB3/CD61) Antibody

CHEMICON®, rabbit polyclonal

Synonym(s):

Platelet Membrane Glycoprotein IIIa, CD61 Antigen

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Product Name

Anti-Integrin β3 Antibody, cytoplasmic domain, serum, Chemicon®

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunoprecipitation (IP): suitable

NCBI accession no.

NM_000212.2

UniProt accession no.

P05106

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... ITGB3(3690)

Immunogen

Synthetic peptide corresponding to the cytoplasmic domain of human integrin beta 3 conjugated to thyroglobulin with gluteraldehyde.

Application

Anti-Integrin β3 Antibody, cytoplasmic domain detects level of Integrin β3 & has been published & validated for use in IP.
Immunoprecipitation

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Integrin beta3.

Preparation Note

Maintain at -20ºC in undiluted aliquots for up to twelve months from date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Replaces: 04-1060

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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James W Frank et al.
Biology of reproduction, 104(3), 657-668 (2020-11-25)
During the peri-implantation period of pregnancy in sheep, there is an initial period of loose apposition of the elongating conceptuses (embryos and associated placental membranes) to the endometrial luminal epithelium (LE) that is followed by adhesion of the conceptus trophectoderm
James W Frank et al.
Reproduction (Cambridge, England), 153(5), 695-706 (2017-03-03)
Attachment of the conceptus trophoblast (Tr) to the uterine luminal epithelium (LE) is critical for successful implantation. This study determined whether alpha v (av) integrins (ITGAV) directly mediate porcine trophoblast cell adhesion to secreted phosphoprotein 1 (SPP1, also known as
Theodore T Wing et al.
Reproduction (Cambridge, England), 159(4), 465-478 (2020-01-29)
Angiogenesis is fundamental to the expansion of the placental vasculature during pregnancy. Integrins are associated with vascular formation; and osteopontin is a candidate ligand for integrins to promote angiogenesis. Endothelial progenitor cells (EPCs) are released from bone marrow into the

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