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Merck

AB2910

Anti-Mcl-1 Antibody

serum, Chemicon®

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Mcl-1 Antibody, serum, Chemicon®

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... MCL1(4170)

Application

Immunoblot 1:2,000

Immunoprecipitation. Precipitates a 37-39 kDa protein, which appears as a doublet in some cells.

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

The following tissues/cells can serve as positive controls: tonsil, tonsillar B cells, B-cell lines Reh, Daudi, and Karpas 422.

Optimal working dilutions for AB2910 must be determined by end user.
Research Category
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
This Anti-Mcl-1 Antibody is validated for use in IP, WB, IH(P) for the detection of Mcl-1.

Biochem/physiol Actions

Recognizes Human Mcl-1. Not reactive with other members of the Bcl-2 family, as verified by immunoblot.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide corresponding to amino acids 121-139 of human Mcl-1.

Physical form

Liquid antiserum.

Preparation Note

Store at -20°C for up to 12 months in undiluted aliquots. Avoid repeated freeze-thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Journal of neuroinflammation, 15(1), 201-201 (2018-07-10)
Following injury to the central nervous system, increased microglia, secretion of pro- and anti-inflammatory cytokines, and altered blood-brain barrier permeability, a hallmark of degeneration, are observed at and immediately adjacent to the injury site. However, few studies investigate how regions

Global Trade Item Number

SKUGTIN
AB291004053252364631

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