AB2994

Anti-Phospho-Bid (Ser65) Antibody

Name: Anti-Phospho-Bid (Ser65) Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Synonym(s):

BH3-interacting domain death agonist, p22 BID, BID

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

western blot: suitable

NCBI accession no.

NM_001196.2

UniProt accession no.

P55957-2

shipped in

wet ice

target post-translational modification

phosphorylation (pSer65)

Gene Information

human ... BID(637)

General description

22 kDa

Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. Bid induces ICE-like proteases and apoptosis. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the major proteolytic product p15 Bid translocates to mitochondria where it triggers cytochrome c release.

Immunogen

Epitope: Ser65

Application

Anti-Phospho-Bid (Ser65) Antibody detects level of Phospho-Bid (Ser65) & has been published & validated for use in WB.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Biochem/physiol Actions

Other species have not been tested.

The antibody reacts with the 22 kDa phospho-Bid-S65 protein.

Physical form

Antigen Affinity Purified

Purified in PBS with 0.09% NaN3.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Western Blot:: Jurkat cell lysate

Evaluated by Western Blot on Jurkat cell lysate treated with (+/-) insulin.

Western Blot Analysis:
A 1:100~500 dilution of this antibody detected phospho-Bid-S65 on jurkat cell lysate treated with (+/-) insulin.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)