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Merck

AB3383-I

Sigma-Aldrich

Anti-UTF1 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

UTF1, Undifferentiated embryonic cell transcription factor 1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, mouse

species reactivity (predicted by homology)

human (based on 100% sequence homology)

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_003568

UniProt accession no.

Q5T230

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... UTF1(8433)

General description

Undifferentiated embryonic cell transcription factor 1 is a nucleus protein encoded by the UTF1 gene in human and functions as a transcriptional coactivator of ATF2. UTF1 is reported to interact with the ATF-2 metal binding motif via the leucine zipper motif within its conserved domain 2 (CD2) and both CD1 & CD2 of UTF1 and also independently mediates association with TATA-binding protein-containing complex. (PMID 9749258)
~48 kDa observed. UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells (Okuda, A., et al. (1998). EMBO. 17(7):2019–2032).

Immunogen

Epitope: Near N-terminus
KLH-conjugated linear peptide corresponding to human UTF1 near N-terminus.

Application

Anti-UTF1 Antibody is an antibody against UTF1 for use in Western Blotting and Immunohistochemistry.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected UTF1 in mouse kidney and rat liver tissue.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Nuclear Receptors

Biochem/physiol Actions

Other homologies: mouse, rat 95%.

Physical form

Affinity
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in mouse embryonic stem cell lysate.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected UTF1 in 10 µg of mouse embryonic stem cell lysate.

Other Notes

Concentration: Please refer to lot specific datasheet.
Replaces: AB3383

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells.
Okuda, A; Fukushima, A; Nishimoto, M; Orimo, A; Yamagishi, T; Nabeshima, Y; Kuro-o et al.
The Embo Journal null

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Global Trade Item Number

SKUGTIN
AB3383-I04055977145014

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