Key Documents
AB3629
Anti-Caspase 9 Antibody, active (cleaved) form
Chemicon®, from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rabbit
Quality Level
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
Gene Information
human ... CASP9(842)
General description
Caspase-9 is an important member of the caspase family. When cytochrome c is released from the mitochondria early upon apoptosis induction, it associates with Apaf-1 and procaspase-9 and forms an apoptosome. This complex cleaves procaspase-9 into a large 37kDa subunit and a small 10kDa subunit.
Immunogen
Epitope: active (cleaved) form
Synthetic peptide. FQEGLRTFDQLD
Application
Anti-Caspase 9 Antibody, active (cleaved) form detects level of Caspase 9 & has been published & validated for use in IP, WB & IC.
Research Category
Apoptosis & Cancer
Metabolism
Apoptosis & Cancer
Metabolism
Research Sub Category
Caspases
Enzymes & Biochemistry
Caspases
Enzymes & Biochemistry
Western blot: 0.5-4 μg/mL
Immunoprecipitation: 10-20 μg/mL
Immunocytochemistry: 10-20 μg/mL
Optimal working dilutions must be determined by end user.
Immunoprecipitation: 10-20 μg/mL
Immunocytochemistry: 10-20 μg/mL
Optimal working dilutions must be determined by end user.
Biochem/physiol Actions
AB3629 detects only the cleaved large 37kDa subunit and does not detect the precursor form in cells undergoing apoptosis. It also does not detect other caspases.
Physical form
Affinity purified immunoglobulin. Liquid in PBS, containing 50% glycerol, 0.5% BSA and 0.02% thimerosal.
Format: Purified
Preparation Note
Maintain frozen at -20°C. For optimal storage, aliquot and freeze at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Replaces: 04-443
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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