AB5052
Anti-Glycine Receptor Antibody
Chemicon®, from rabbit
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, mouse, human
manufacturer/tradename
Chemicon®
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... GLRB(2743)
Immunogen
Peptide from the amino terminus of the human alpha1 glycine receptor subunit conjugated to KLH.
Application
Anti-Glycine Receptor Antibody detects level of Glycine Receptor & has been published & validated for use in IP & WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Western blot: 1:1000 using ECL
Immunoprecipitation: 1:10 following the protocol of Raymond et al., Nature (1993) 361:637-641.
Optimal working dilutions must be determined by the end user.
Immunoprecipitation: 1:10 following the protocol of Raymond et al., Nature (1993) 361:637-641.
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Recognizes glycine receptor alpha1. Shows cross reactivity to glycine receptor alpha2. subunits The antibody has been used successfully in Western blot and immunoprecipitation assays with cell extracts containing recombinant human glycine receptors and with homogenates of mouse spinal cord. By Western blot the antibody recognizes a protein with a molecular weight of ~ 48 kD.
Physical form
Affinity purified immunoglobulin. Lyophilized from ammonium bicarbonate (5mM) some residual salt may be present. Reconstitute with 100 μL of PBS. Contains no preservatives.
Preparation Note
Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Differential plasticity of the GABAergic and glycinergic synaptic transmission to rat lumbar motoneurons after spinal cord injury.
Sadlaoud, K; Tazerart, S; Brocard, C; Jean-Xavier, C; Portalier, P; Brocard, F; Vinay, L; Bras, H
The Journal of Neuroscience null
Joan S Baizer et al.
Frontiers in neuroanatomy, 18, 1331230-1331230 (2024-03-01)
Auditory information is relayed from the cochlea via the eighth cranial nerve to the dorsal and ventral cochlear nuclei (DCN, VCN). The organization, neurochemistry and circuitry of the cochlear nuclei (CN) have been studied in many species. It is well-established
Karina Sadlaoud et al.
Journal of chemical neuroanatomy, 106, 101787-101787 (2020-04-28)
Spasticity is a disabling motor disorder affecting 70% of people with brain and spinal cord injury. The rate-dependent depression (RDD) of the H reflex is the only electrophysiological measurement correlated with the degree of spasticity assessed clinically in spastic patients.
Wen Zhou et al.
International journal of molecular medicine, 38(5), 1481-1489 (2016-12-28)
The medial vestibular nucleus (MVN) and the cerebellar flocculus have been known to be the key areas involved in vestibular compensation (VC) following unilateral labyrinthectomy (UL). In this study, we examined the role of gephyrin and glycine receptor (GlyR) in VC using Sprague-Dawley rats
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB5052 | 04053252729744 |
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