Anti-Melanocortin Receptor-1 Antibody

Anti-Melanocortin Receptor-1 Antibody is an antibody against Melanocortin Receptor-1 for use in ELISA & WB.

Research Category
Neuroscience

Research Sub Category
CNS Control of Metabolism

Hormones & Receptors

Western blot: 1-10 μg/mL using Chemiluminescence technique

ELISA: 1:10,000 - 100,000



Optimal working dilutions must be determined by end user.

Melanocyte Stimulating Hormone Receptor (MSH-R), also called Melanotropin Receptor, or Melanocortin-1 Receptor (MC1-R), is a 315 aa transmembrane protein belonging to the family 1 of G-Protein coupled receptors. It is a receptor for MSH (a, b, g) and ACTH. Its activity is mediated by G-proteins that activate adenylate cyclase. It is found in Melanocytes and corticoadrenal tissue as well as various tissues like adrenal gland, leukocytes, lung, lymph node, ovary, testis, pituitary, placenta, spleen and uterus.

Mouse MSH-R. Reactivity with other species has not been confirmed. The immunogen sequence shows 70% homology with human, 66% with bovine, sheep and horse, and 60% with canine.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

A 21 mer peptide (designated MCR11) from the 3rd cytoplasmic domain of mouse MC1-R.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Affinity Purified immunoglobulin. Liquid in PBS, 0.1% BSA and 0.05% sodium azide.

Can be refrigerated at 2-8°C in undiluted aliquots for short term use. Maintain frozen at -20°C in undiluted aliquots for up to 12 months.

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany