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Merck

AB5566

Anti-Capsaicin Receptor Antibody, CT

serum, Chemicon®

Synonym(s):

Vanilloid Receptor 1, VR1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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Product Name

Anti-Capsaicin Receptor Antibody, CT, serum, Chemicon®

biological source

guinea pig

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... TRPV1(7442)

Analysis Note

Control
Immunogen peptide (catalog number AG298) is available for preadsorbtion control studies.

Application

Anti-Capsaicin Receptor Antibody, C-terminus detects level of Capsaicin Receptor & has been published & validated for use in IH.
Immunohistochemistry: 1:1,000. The antibody reacts well with tissue from the rat dorsal root ganglia.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Recognizes Capsaicin Receptor (Vanilloid Receptor 1, VR1).

Immunogen

A 22 amino acid peptide corresponding to the C-terminus of the rat Capsaicin Receptor protein (Catalog number AG298).

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Serum. Liquid. Contains less than 0.02% sodium azide.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 1


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yumi Matsushita et al.
The Journal of veterinary medical science, 83(10), 1570-1581 (2021-09-03)
The activation of α2 adrenergic receptors contributes to analgesia not only in the central nervous system but also in the peripheral nervous system. We reported that noradrenaline inhibits the activity of transient receptor potential vanilloid 1 (TRPV1) evoked by capsaicin
S-Q He et al.
Neuroscience, 261, 43-51 (2014-01-01)
Mas-related G-protein-coupled receptor subtype C (MrgC) may play an important role in pain sensation. However, the distribution of MrgC receptors in different subpopulations of rodent dorsal root ganglion (DRG) neurons has not been clearly demonstrated owing to a lack of
Sam M Hermes et al.
Journal of chemical neuroanatomy, 72, 1-7 (2015-12-27)
The vagus nerve is dominated by afferent fibers that convey sensory information from the viscera to the brain. Most vagal afferents are unmyelinated, slow-conducting C-fibers, while a smaller portion are myelinated, fast-conducting A-fibers. Vagal afferents terminate in the nucleus tractus
Shuohao Sun et al.
Neuron, 93(4), 840-853 (2017-02-24)
Coding of itch versus pain has been heatedly debated for decades. However, the current coding theories (labeled line, intensity, and selectivity theory) cannot accommodate all experimental observations. Here we identified a subset of spinal interneurons, labeled by gastrin-releasing peptide (Grp)
Shuang-quan Yu et al.
Acta pharmacologica Sinica, 32(6), 845-852 (2011-06-07)
To investigate the effects of selective knockdown of TRPV1 channels in the lower thoracic and upper lumbar segments of spinal cord, dorsal root ganglia (DRG) and mesenteric arteries on rat blood pressure responses to high salt intake. TRPV1 short-hairpin RNA

Global Trade Item Number

SKUGTIN
AB556604053252511158

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