AB5802
Anti-Dopamine Transporter Antibody, extracellular Loop 2
Chemicon®, from rabbit
Synonym(s):
Anti-DAT
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, monkey
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... SLC6A3(6531)
Immunogen
Epitope: extracellular Loop 2
Synthetic peptide from the EL2 region of human dopamine transporter.
Application
Anti-Dopamine Transporter Antibody, extracellular Loop 2 is an antibody against Dopamine Transporter for use in IH & WB.
Immunoblotting: 1:500-1:1,000
Immunohistochemistry using formaldehyde-fixed brain sections: 1:500-1:1,000
Optimal working dilutions must be determined by the end user.
Immunohistochemistry using formaldehyde-fixed brain sections: 1:500-1:1,000
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Biochem/physiol Actions
Dopamine Transporter, Extracellular loop 2 (EL2).
Physical form
Affinity purified immunoglobulin. Each vial contains ~33 μg of affinity-purified antibody in 100 μL of 10 mM HEPES (pH 7.5), 150 mM NaCl with 100 μg/mL BSA and 50% glycerol.
Preparation Note
Maintain at -20 to -80°C in undiluted aliquots for up to six months. Store in a NON-self-defrosting freezer. Avoid repeated freeze-thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Certificates of Analysis (COA)
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Adithya Gopinath et al.
NPJ Parkinson's disease, 8(1), 72-72 (2022-06-08)
Parkinson's disease (PD) is marked by a loss of dopamine neurons, decreased dopamine transporter (DAT) and tyrosine hydroxylase (TH) expression. However, this validation approach cannot be used for diagnostic, drug effectiveness or investigational purposes in human patients because midbrain tissue
Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3.
Ega?a, LA; Cuevas, RA; Baust, TB; Parra, LA; Leak, RK; Hochendoner, S; Pe?a, K; Quiroz et al.
The Journal of Neuroscience null
Etienne Cartier et al.
Frontiers in cellular neuroscience, 13, 35-35 (2019-03-05)
The dopamine transporter (DAT) is a plasma membrane protein responsible for the uptake of released dopamine back to the presynaptic terminal and ending dopamine neurotransmission. The DAT is the molecular target for cocaine and amphetamine as well as a number
Abeer Dagra et al.
NPJ Parkinson's disease, 7(1), 76-76 (2021-08-20)
Pathophysiological damages and loss of function of dopamine neurons precede their demise and contribute to the early phases of Parkinson's disease. The presence of aberrant intracellular pathological inclusions of the protein α-synuclein within ventral midbrain dopaminergic neurons is one of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| AB5802 | 04053252269080 |
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