AB5848

Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat

Name: Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat
Brand: MM

Chemicon^®, from rabbit

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About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Product Name

Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat, Chemicon^®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, rat

manufacturer/tradename

Chemicon^®

technique(s)

western blot: suitable

NCBI accession no.

NM_005458.5

UniProt accession no.

O75899

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... GABBR2(9568)

Application

Immunoblotting: 1:500-1:1,000. Membrane preparations with proteinase inhibitors are recommended. Whole rat brain membrane preparations. The antibody detects a ~105kDa band under standard western conditions. The immunogen used is 100% conserved in human by sequence analysis; other species have not been examined for reactivity or homology.

Optimal working dilutions must be determined by end user.

Research Category
Neuroscience

Research Sub Category
Neurotransmitters & Receptors

This Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat is validated for use in WB for the detection of GABA B Receptor R2.

Biochem/physiol Actions

GABAB Receptor R2 subunit, N-terminus. No reactivity with GABABR1 has been detected.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The inhibitory neurotransmitter, GABA, acts through two ligand-gated channels, GABA(A) and GABA© receptors and GABA(B), the latter of which acts through a G protein mechanism. GABA(B)R2 is one of the two G-protein coupled receptors for GABA(B) that acts as a heteromeric assembly with GABA(B)R1.

Immunogen

Epitope: a.a. 42-54 rat

peptide residues 42-54 of the rat 105 kDa GABA(b)R2 protein

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified

Purified immunoglobulin. Liquid. Buffer = PBS containing 0.02% sodium azide.

Preparation Note

Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Distribution and function of GABAB receptors in spider peripheral mechanosensilla.

Panek, I; Meisner, S; Torkkeli, PH

Journal of Neurophysiology null

Differential trafficking of AMPA and NMDA receptors during long-term potentiation in awake adult animals.

Williams, JM; Guevremont, D; Mason-Parker, SE; Luxmanan, C; Tate, WP; Abraham, WC

The Journal of Neuroscience null

Global Trade Item Number

SKU	GTIN
AB5848	04053252275708

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