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AB9328

Anti-Thioredoxin 1 Antibody

serum, Chemicon®

Synonym(s):

TRX1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
2
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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, rat

species reactivity (predicted by homology)

human (sequence homology 14/15)

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_005933.2, NM_024891.1

UniProt accession no.

Q6P902

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... TXN(7295)

Immunogen

Synthetic peptide from rat/mouse Thioredoxin 1.

Application

Detect Thioredoxin 1 using this Anti-Thioredoxin 1 Antibody validated for use in WB.
Immunoblotting: 1:1,000-1:5,000 using ECL. Reacts with the ~12-14 kD thioredoxin 1 protein. Additional bands >30 kD may been seen.

Suggested dilution and blocking buffer is TBST containing 5% non-fat milk. Suggested gel percentage is 15%. Suggested incubation time is overnight.
Research Category
Neuroscience
Research Sub Category
Oxidative Stress

Biochem/physiol Actions

Recognizes Thioredoxin 1 (TRX1).

Physical form

Rabbit serum. Liquid. Contains no preservative.

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Other Notes

Replaces: MABN1090

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Related Content

White Paper- Modern Methods in Oxidative Stress Research

"Redox reactions are powerful chemical processes that involve the reduction and oxidation of proteins and metabolites found in living things. The mechanisms that regulate them are key to maintaining homeostasis and the balance between good health and disease pathology. Oxidative stress is the state where the delicate balance of redox biology is upset, and the pathology of oxidative stress are the cellular consequences to such an imbalance."

RABBIT ANTI-THIOREDOXIN 1
PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD
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Xiaoqin Zhao et al.
Acta biochimica et biophysica Sinica, 46(4), 318-329 (2014-03-01)
Cardiac complications are the leading cause of death in diabetes. However, the mechanism of diabetes in inducing myocardial injury and apoptosis, and whether the thioredoxin (Trx) system is involved remain unclear. In this study, male Sprague-Dawley rats were randomly divided
Chiara Milanese et al.
Nature communications, 10(1), 4887-4887 (2019-10-28)
Accumulation of DNA lesions causing transcription stress is associated with natural and accelerated aging and culminates with profound metabolic alterations. Our understanding of the mechanisms governing metabolic redesign upon genomic instability, however, is highly rudimentary. Using Ercc1-defective mice and Xpg

Global Trade Item Number

SKUGTIN
AB932804053252324673