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Merck

AB9754

Anti-Kisspeptin Antibody

serum, Chemicon®

Synonym(s):

kp10

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-Kisspeptin Antibody, serum, Chemicon®

biological source

rabbit

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

sheep, rat, mouse

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable
radioimmunoassay: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

Application

Anti-Kisspeptin Antibody detects level of Kisspeptin & has been published & validated for use in IH, RIA.
Immunohistochemistry on 4% paraformaldehyde fixed tissue: 1:500-1:1,000 (PAP and ABC with NiDAB detection system).

RIA: 1:500-1:10,000

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Hormones & Receptors

CNS Control of Metabolism

Biochem/physiol Actions

Kisspeptin 10 (kp10, metastin). No cross reactivity with GnRH, Galatin, SP, NPY, CRH, alphaMSH, SRIF or PrRP by RIA.
The antibody showed a very low level of reactivity with human kp10.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Peptide from mouse kisspeptin 10. The sequence is common to all kisspeptin isoforms.

Physical form

Rabbit serum.Liquid containing 50% glycerol, Ph 7.4, Phosphate buffer 0.01M.
Serum

Preparation Note

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 2


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anabolic androgenic steroid abuse: multiple mechanisms of regulation of GABAergic synapses in neuroendocrine control regions of the rodent forebrain.
J G Oberlander,D M Porter,C A A Penatti,L P Henderson
Journal of Neuroendocrinology null
Arcuate kisspeptin/neurokinin B/dynorphin (KNDy) neurons mediate the estrogen suppression of gonadotropin secretion and body weight.
Mittelman-Smith, MA; Williams, H; Krajewski-Hall, SJ; Lai, J; Ciofi, P; McMullen, NT; Rance, NE
Endocrinology null
Characterisation of Arcuate Nucleus KisspeptinNeurokinin B Neuronal Projections and Regulation during Lactation in the Rat.
True C
Journal of Neuroendocrinology null
Kisspeptin immunoreactive cells of the ovine preoptic area and arcuate nucleus co-express estrogen receptor alpha.
Franceschini, I, et al.
Neuroscience Letters, 401, 225-230 (2006)
Leptin deficiency and diet-induced obesity reduce hypothalamic kisspeptin expression in mice.
Quennell, JH; Howell, CS; Roa, J; Augustine, RA; Grattan, DR; Anderson, GM
Endocrinology null

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