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Merck

ABC335

Anti-MTCH2 Antibody

from rabbit, purified by affinity chromatography

Synonym(s):

MTCH2, Mitochondrial carrier homolog 2, HSPC032, MIMP, Met-induced mitochondrial protein

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IF, IHC, WB
Citations:
-
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, human

technique(s)

immunofluorescence: suitable, immunohistochemistry: suitable, western blot: suitable

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... MTCH2(23788)

General description

Mitochondrial carrier homolog 2 (MTCH2) may play a key role in the mitochondrial apoptosis pathway and may induce mitochondrial depolarization. MTCH2 is suggested to catalyze the exchange of substrates across the inner mitochondrial membrane in response to apoptotic signals. Additionally, it is suggested to be targeted by Bid, a pro-apoptotic Bcl-2 family member. The Bcl-2 family of proteins incorporates a number of critical regulators of apoptosis that can be divided into two classes: inhibitors of apoptosis and promoters of cell death. Apoptosis plays a major role in tissue homeostasis, normal organism development, and removal of damaged cells. The disruption of this process has been linked to a variety of diseases such as cancer.
~34 kDa observed.

Immunogen

KLH-conjugated linear peptide corresponding to human MTCH2.

Application

Anti-MTCH2 Antibody is a highly specific rabbit polyclonal antibody, that targets Mitochondrial carrier homolog 2 & has been tested in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected MTCH2 in mouse kidney tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected MTCH2 in mouse kidney cells.

Analysis Note

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected MTCH2 in 15 µg of HEK293 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.


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wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Storage Class

12 - Non Combustible Liquids



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKUGTIN
ABC33504053252905070