ABC447
Anti-MACC1 Antibody
from rabbit, purified by affinity chromatography
Synonym(s):
Metastasis-associated in colon cancer protein 1, MACC1, SH3 domain-containing protein 7a5
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... MACC1(346389)
General description
Metastasis-associated in colon cancer protein 1 (UniProt Q6ZN28; also known as Putative binding protein 7a5, SH3 domain-containing protein 7a5) is encoded by the MACC1 gene (also known as 7A5, SH3BP4L) (Gene ID 346389) in human. MACC1 is an oncogenic transcription activator that was initially detected in colon cancer. Ongoing studies also establish a strong association between MACC1 upregulation and tumor metastasis, progression, and poor prognosis in many other types of cancers, including cervical cancer, epithelial ovarian cancer, hepatocellular carcinoma, rectal cancer, pancreatic cancer, lung cancer, nasopharyngeal carcinoma, breast cancer, osteosarcoma, glioma, esophageal cancer, gastric cancer, and in non-small cell lung cancer (NSCLC).
~90 kDa observed
Immunogen
GST-tagged recombinant protein corresponding to the C-terminus of human MACC1.
Application
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected MACC1 in human lung, colon, and breast cancer tumor cells.
This Anti-MACC1 Antibody is validated for use in Western Blotting, Immunohistochemistry for the detection of MACC1 .
Analysis Note
Evaluated by Western Blotting in SW620 cell lysate.
Western Blotting Analysis: 0.25 µg/mL of this antibody detected MACC1 in 10 µg of SW620 cell lysate.
Western Blotting Analysis: 0.25 µg/mL of this antibody detected MACC1 in 10 µg of SW620 cell lysate.
Other Notes
Concentration: Please refer to lot specific datasheet.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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