ABC970
Anti-Syntaxin 17 Antibody
from rabbit, purified by affinity chromatography
Synonym(s):
Syntaxin 17
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... STX17(55014)
General description
Syntaxin-17 (UniProt P56962) is encoded by the STX17 gene (Gene ID 55014) in human. Syntaxin-17 belongs to the Soluble N-ethylmaleimide-sensitive factor (NSF) attachment protein receptor (SNARE) family of proteins that mediate membrane fusion events. Syntaxin-17 functions as the autophagosomal Qa-SNARE required for autophagosome-lysosome fusion and it mediates the fusion process by binding to its partner SNAREs, synaptosomal-associated protein 29 (SNAP29; Qbc-SNARE), and vesicle-associated membrane protein 8 (VAMP8; R-SNARE). In addition, the homotypic fusion and protein sorting (HOPS) complex is reported to interact with Syntaxin-17 and promotes Syntaxin-17-dependent autophagosome-lysosome fusion.
~38 kDa observed. Uncharacterized band(s) may appear in some lysates.
Immunogen
Epitope: cytoplasmic domain
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Syntaxin 17.
Application
Immunohistochemistry Analysis: A 1:50-250 dilution from a representative lot detected Syntaxin 17 in human kidney and human adrenal gland tissue.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
This Anti-Syntaxin 17 Antibody is validated for use in Western Blotting, Immunohistochemistry for the detection of Syntaxin 17.
Physical form
Affinity purified
Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Preparation Note
Stable for 1 year at 2-8°C from date of receipt.
Analysis Note
Evaluated by Western Blotting in human adrenal tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected Syntaxin 17 in 10 µg of human adrenal tissue lysate.
Western Blotting Analysis: 2.0 µg/mL of this antibody detected Syntaxin 17 in 10 µg of human adrenal tissue lysate.
Other Notes
Concentration: Please refer to lot specific datasheet.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Still not finding the right product?
Try our Product Selector Tool to narrow your options
Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.