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Merck

ABD85

Anti-PAX3/7BP Antibody

serum, from rabbit

Synonym(s):

PAX3 binding protein 1, PAX7 binding protein 1, GC-rich sequence DNA-binding factor 1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Product Name

Anti-PAX3/7BP Antibody, serum, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, mouse, human

technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

UniProt accession no.

Q9Y5B6

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

mouse ... Paxbp1(67367)

Analysis Note

Evaluated by Western Blot in a jurkat cell lysate.
Western Blot Analysis: A 1:1000 dilution of this antibody detected Pax3/7BP in a 10 µg jurkat cell lysate.

Application

Anti-PAX3/7BP Antibody is an antibody against PAX3/7BP for use in western blotting & IP.
Research Category
Stem Cell Research
Research Sub Category
Muscle Physiology

Developmental Signaling

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

In skeletal muscles, Pax7 uniquely marks muscle satellite cells and plays some important yet unknown functions at the perinatal stage. Pax3/7BP is a ubiquitously expressed nuclear protein, enriched in Pax7+ muscle precursor cells (MPCs), and serves as an indispensable adaptor for Pax7 to recruit the histone-3-lysine-4 (H3K4) methyltransferase (HMT) complex by bridging Pax7 and Wdr5. Recently, Wu et al. have established Pax3/7BP as an essential adaptor linking Pax3/7 with the H3K4 HMT to regulate the proliferation of muscle progenitor cells.
~105 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Immunogen

Recombinant protein corresponding to mouse PAX3/7BP.

Physical form

Unpurified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

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Storage Class

10 - Combustible liquids

wgk

WGK 1

Certificates of Analysis (COA)

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Global Trade Item Number

SKUGTIN
ABD8504053252939563

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