ABE467
Anti-MSL3-like 1 Antibody
from rabbit
Synonym(s):
Male-specific lethal 3 homolog, Male-specific lethal-3 homolog 1, Male-specific lethal-3 protein-like 1, MSL3-like 1
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ChIP, WB
Citations:
2
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
technique(s)
ChIP: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... MSL3(10943)
General description
MSL3, also known as Male-specific lethal 3 homolog, or Male-specific lethal-3 homolog 1, or Male-specific lethal-3 protein-like 1 (MSL3-like 1), and encoded by the gene MSL3/MSL3L1, is a component of the MSL(male-specific lethal ) histone acetyltransferase complex which is responsible for the majority of histone H4 acetylation at ′Lys-16′ which is implicated in the formation of higher-order chromatin structure. MSL3 may also be involved in chromatin remodeling and transcriptional regulation. Additionally, MSL3 may have a role in X inactivation as its gene is a target for X inactivation. MSL3 is localized to the nucleus. MSL3 is expressed in many tissues including liver, pancreas, heart, lung, kidney, skeletal muscle, brain, and placenta, with highest expression in skeletal muscle and heart.
~58 kDa observed. Five isoforms are known to exist at 60 kDa (isoform 1), 53 kDa (isoform 2), 58 kDa (isoform 3), 40 kDa (isoform 4), and 48 kDa (isoform 5).
Immunogen
Linear peptide corresponding to human MSL3-like 1.
Application
Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated MSL3-like 1 from HeLa cell lysate (Wu, L., et al. (2011). Mol Cell. 43(1):132-144.).
Detect MSL3-like 1 using this Anti-MSL3-like 1 antibody validated for use in western blotting & ChIP.
Physical form
Format: Purified
Analysis Note
Evaluated by Western Blotting in Jurkat cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected MSL3-like 1 in 10 µg of Jurkat cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected MSL3-like 1 in 10 µg of Jurkat cell lysate.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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