ABE480

Anti-Centrin-2 Antibody

Name: Anti-Centrin-2 Antibody
Brand: MM

serum, from rabbit

Synonym(s):

Centrin-2, Caltractin isoform 1

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse, rat

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

NCBI accession no.

NP_004335

UniProt accession no.

P41208

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CETN2(1069)

General description

Centrin-2 is also called Caltractin isoform 1. Centrin-2 is involved in microtubule organization, structure and function, and is required for centriole duplication and spindle formation. Centrin-2 also has a role in regulating cytokinesis, genome stability and global genome nucleotide excision repair (GG-NER) as component of the XPC complex.

~18 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.

Immunogen

Recombinant protein corresponding to human Centrin-2.

Application

Anti-Centrin-2 Antibody is a highly specific rabbit polyclonal antibody, that targets Centrin & has been tested in western blotting, ICC, IHC & IP.

Immunocytochemistry Analysis: A representative lot from an independent laboratory detected Centrin-2 in MDCK cells (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).

Immunohistochemistry Analysis: A representative lot from an independent laboratory detected Centrin-2 in wild type and galectin-3 null mouse kidney tissues (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).

Immunoprecipitation Analysis: A representative lot from an independent laboratory immunoprecipitated Centrin-2 in MDCK cell lysate (Koch, A., et al. (2010). Mol Biol Cell. 21(2):219-231.).

Analysis Note

Evaluated by Western Blotting in Jurkat cell lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Centrin-2 in 10 µg of Jurkat cell lysate.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Immunogold Localization of Molecular Constituents Associated with Basal Bodies, Flagella, and Extracellular Matrices in Male Gametes of Land Plants.

Renee A Lopez et al.

Bio-protocol, 7(21), e2599-e2599 (2017-11-05)

Male gametes (spermatozoids) are the only motile cells produced during the life cycle of land plants. While absent from flowering and most cone-bearing plants, motile cells are found in less derived taxa, including bryophytes (mosses, liverworts and hornworts), pteridophytes (lycophytes

Replication collisions induced by de-repressed S-phase transcription are connected with malignant transformation of adult stem cells.

Ting Zhang et al.

Nature communications, 13(1), 6907-6907 (2022-11-15)

Transcription replication collisions (TRCs) constitute a major intrinsic source of genome instability but conclusive evidence for a causal role of TRCs in tumor initiation is missing. We discover that lack of the H4K20-dimethyltransferase KMT5B (also known as SUV4-20H1) in muscle

Global Trade Item Number

SKU	GTIN
ABE480	04053252913938

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