ABE492

Anti-Histone lysine demethylase NO66 Antibody

Name: Anti-Histone lysine demethylase NO66 Antibody
Brand: MM

from rabbit, purified by affinity chromatography

Synonym(s):

Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, 60S ribosomal protein L8 histidine hydroxylase, Histone lysine demethylase NO66, Myc-associated protein with JmjC domain, Nucleolar protein 66, hsNO66, Ribosomal oxygenase NO66, ROX,

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About This Item

UNSPSC Code:

12352203

eCl@ss:

32160702

NACRES:

NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

technique(s)

western blot: suitable

NCBI accession no.

NP_078920

UniProt accession no.

Q9H6W3

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... RIOX1(79697)

General description

NO66 is a lysine-specific demethylase that removes methyl groups from histone H3 at lysine 4 and lysine 36. This enzyme has been shown to more readily demethylate trimethylated H3 ′Lys-4′ (H3K4me3) and monomethylated H3 Lys4 (H3K4me1) consistent with its role in modulating the histone code. This protein is a highly conserved, constitutive nucleolar component that shows a dual localization pattern with strong enrichment in the granular part of nucleoli and in distinct nucleoplasmic entities.

~66 kDa observed

Immunogen

Epitope: Near N-terminus

KLH-conjugated linear peptide corresponding to human Histone lysine demethylase NO66 near the N-terminus.

Application

Detect NO66 using this rabbit polyclonal antibody, Anti-Histone lysine demethylase NO66 Antibody validated for use in western blotting.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

Biochem/physiol Actions

This antibody recognizes Histone lysine demethylase NO66 near the N-terminus.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
A431 cell lysate

Evaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Histone lysine demethylase NO66 in 10 µg of A431 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Global Trade Item Number

SKU	GTIN
ABE492	04053252910814

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